Understanding ACES Buffer Properties for Optimal Research Outcomes
For any researcher working with biological systems, understanding the properties of the reagents they use is fundamental to achieving accurate and reproducible results. ACES (N-(2-Acetamido)-2-aminoethanesulfonic acid), identified by CAS number 7365-82-4, is a widely used zwitterionic buffer that offers distinct advantages in various scientific disciplines. Its chemical structure and behavior dictate its suitability for applications ranging from cell culture to intricate biochemical analyses.
The primary appeal of ACES lies in its buffering capacity, providing stable pH control within a useful range of approximately 6.1 to 7.5. This pH range is particularly relevant for many biological processes that occur under near-neutral conditions. Researchers commonly seek ACES for tasks requiring precise pH maintenance, such as enzymatic assays, protein electrophoresis, and the preparation of physiological buffers. When considering how to buy ACES buffer, understanding its pKa value is important, as it informs the optimal buffering range.
A notable characteristic of ACES, shared by many Good's buffers, is its zwitterionic nature. This means that at neutral pH, the molecule carries both a positive and a negative charge, contributing to its high solubility in water and its reduced interaction with biological macromolecules compared to ionic buffers. This property makes it an excellent choice for studies where minimizing buffer interference is critical. However, it's also important to note that ACES can form complexes with certain metal ions, such as copper (Cu) and magnesium (Mg), with weaker interactions with calcium (Ca), manganese (Mn), cobalt (Co), and nickel (Ni). Researchers working with solutions containing these metal ions should take these interactions into account and consider the implications for their experimental design.
When procuring ACES, purity is a key factor. A purity of ≥99% is typically recommended for most biochemical and molecular biology applications to prevent any confounding effects from impurities. Scientists often look for ACES price information from various suppliers to ensure they are getting good value for their investment. As a dedicated manufacturer and supplier, we focus on providing high-purity ACES at competitive prices, ensuring that researchers have access to a reliable and cost-effective reagent.
For those requiring ACES for cell culture media, electrophoresis, or other biochemical research needs, partnering with a reputable manufacturer and supplier is essential. Understanding the complete property profile of ACES allows researchers to leverage its benefits effectively and avoid potential pitfalls. We are committed to supplying high-quality ACES, supported by comprehensive technical data, to facilitate your research endeavors and contribute to scientific advancement.
Perspectives & Insights
Silicon Analyst 88
“Researchers commonly seek ACES for tasks requiring precise pH maintenance, such as enzymatic assays, protein electrophoresis, and the preparation of physiological buffers.”
Quantum Seeker Pro
“When considering how to buy ACES buffer, understanding its pKa value is important, as it informs the optimal buffering range.”
Bio Reader 7
“A notable characteristic of ACES, shared by many Good's buffers, is its zwitterionic nature.”