In the realm of organic synthesis, specific reagents are pivotal for achieving complex molecular transformations. 1,1'-(Azodicarbonyl)dipiperidine (ADDP), identified by CAS number 10465-81-3, is a prime example of such a reagent, widely recognized for its efficacy in the Mitsunobu reaction. For procurement professionals and research chemists, a thorough understanding of ADDP's properties and applications, coupled with insights into purchasing considerations, is vital. NINGBO INNO PHARMCHEM CO.,LTD., as a specialized chemical manufacturer and supplier, aims to provide clarity on this essential compound.

Key Properties of 1,1'-(Azodicarbonyl)dipiperidine (ADDP)

ADDP typically presents as a pale yellow to yellow solid. Its chemical structure makes it an effective azodicarboxylate for the Mitsunobu reaction, where it works in conjunction with phosphines to facilitate nucleophilic substitution reactions with inversion of stereochemistry. Its solubility characteristics, often described as soluble in organic solvents like chloroform and slightly soluble in methanol, are important for reaction setup. When you are considering to buy ADDP, understanding these physical properties helps in planning your experimental procedures.

Diverse Applications in Chemical Synthesis

The primary application for ADDP lies in the Mitsunobu reaction, enabling:

  • Stereoselective Alcohol Inversion: Crucial for chiral synthesis in pharmaceuticals and fine chemicals.
  • Ester and Ether Formation: Facilitates mild and efficient formation of these common functional groups.
  • Synthesis of Heterocycles: Used in creating cyclic organic compounds with diverse applications.

Beyond the Mitsunobu reaction, ADDP finds use in various other synthetic sequences, making it a versatile tool for chemists. Researchers looking to purchase ADDP for specific research projects can count on its broad applicability.

Purchasing Considerations for ADDP

When procuring ADDP, several factors are essential for B2B clients:

  1. Purity: For reliable results, especially in pharmaceutical research, high purity (e.g., >98%) is non-negotiable. Always check the specifications provided by the manufacturer or supplier.
  2. Supplier Reliability: Partnering with a reputable manufacturer ensures consistent quality, availability, and timely delivery. NINGBO INNO PHARMCHEM CO.,LTD. prides itself on being a dependable supplier.
  3. Pricing: Direct sourcing from manufacturers in China often provides significant cost advantages for bulk purchases. It is wise to obtain quotes from multiple suppliers but prioritize overall value, which includes quality and service.
  4. Technical Documentation: Ensure that the supplier provides necessary documentation such as Certificates of Analysis (CoA) and Safety Data Sheets (SDS).

NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-quality 1,1'-(Azodicarbonyl)dipiperidine to meet the diverse needs of the chemical industry. We encourage you to contact us for pricing and to discuss how our ADDP can support your synthetic endeavors. Buying from a trusted source simplifies your procurement process and assures the quality of your chemical inputs.