Understanding Benzene Metabolites: The Role of 1,2,4-Benzenetriol
Benzene, a ubiquitous industrial solvent and component of gasoline, is a known human carcinogen. Understanding its metabolic pathways within the body is crucial for assessing its health risks. A key compound involved in these pathways is 1,2,4-Benzenetriol (CAS 533-73-3), also referred to as hydroxyquinol. Its study is vital for toxicological research and the broader field of environmental health.
NINGBO INNO PHARMCHEM CO.,LTD., a dedicated manufacturer of fine chemicals in China, provides high-purity 1,2,4-Benzenetriol, which serves as a crucial reference standard and research tool for scientists investigating benzene's effects. Access to this chemical from reliable suppliers is fundamental for accurate scientific inquiry.
When benzene is absorbed into the body, it undergoes enzymatic transformations, primarily mediated by cytochrome P450 enzymes. This process generates various reactive intermediates, including phenols and quinones, which are subsequently conjugated and excreted. 1,2,4-Benzenetriol emerges as one of the metabolites in this cascade, formed through the hydroxylation of hydroquinone, another benzene metabolite. Its presence and reactivity are considered significant factors in the potential toxicity associated with benzene exposure.
Research into 1,2,4-Benzenetriol has highlighted its ability to form reactive oxygen species (ROS) and its potential genotoxicity, including DNA damage. These findings underscore the importance of controlling benzene exposure in occupational settings and the environment. For researchers in toxicology, a consistent and pure supply of 1,2,4-Benzenetriol from a reputable source like NINGBO INNO PHARMCHEM CO.,LTD. is indispensable for conducting in vitro and in vivo studies.
The ability to buy 1,2,4-Benzenetriol from established Chinese manufacturers like us ensures that laboratories have access to the materials needed for critical safety assessments and pathway analysis. Our commitment to quality means that researchers can rely on the compound's integrity for their experiments.
Beyond its role as a benzene metabolite, 1,2,4-Benzenetriol also finds applications in other chemical synthesis routes, as previously discussed. However, its connection to benzene metabolism places it within a critical area of public health and safety research.
NINGBO INNO PHARMCHEM CO.,LTD. is committed to supporting scientific advancement by supplying high-quality 1,2,4-Benzenetriol. We understand the importance of this compound in toxicological research and strive to be a dependable partner for the scientific community worldwide.
In essence, 1,2,4-Benzenetriol serves as a critical marker and participant in the complex metabolic processing of benzene, making its study vital for understanding and mitigating the health risks associated with this common environmental contaminant.
NINGBO INNO PHARMCHEM CO.,LTD., a dedicated manufacturer of fine chemicals in China, provides high-purity 1,2,4-Benzenetriol, which serves as a crucial reference standard and research tool for scientists investigating benzene's effects. Access to this chemical from reliable suppliers is fundamental for accurate scientific inquiry.
When benzene is absorbed into the body, it undergoes enzymatic transformations, primarily mediated by cytochrome P450 enzymes. This process generates various reactive intermediates, including phenols and quinones, which are subsequently conjugated and excreted. 1,2,4-Benzenetriol emerges as one of the metabolites in this cascade, formed through the hydroxylation of hydroquinone, another benzene metabolite. Its presence and reactivity are considered significant factors in the potential toxicity associated with benzene exposure.
Research into 1,2,4-Benzenetriol has highlighted its ability to form reactive oxygen species (ROS) and its potential genotoxicity, including DNA damage. These findings underscore the importance of controlling benzene exposure in occupational settings and the environment. For researchers in toxicology, a consistent and pure supply of 1,2,4-Benzenetriol from a reputable source like NINGBO INNO PHARMCHEM CO.,LTD. is indispensable for conducting in vitro and in vivo studies.
The ability to buy 1,2,4-Benzenetriol from established Chinese manufacturers like us ensures that laboratories have access to the materials needed for critical safety assessments and pathway analysis. Our commitment to quality means that researchers can rely on the compound's integrity for their experiments.
Beyond its role as a benzene metabolite, 1,2,4-Benzenetriol also finds applications in other chemical synthesis routes, as previously discussed. However, its connection to benzene metabolism places it within a critical area of public health and safety research.
NINGBO INNO PHARMCHEM CO.,LTD. is committed to supporting scientific advancement by supplying high-quality 1,2,4-Benzenetriol. We understand the importance of this compound in toxicological research and strive to be a dependable partner for the scientific community worldwide.
In essence, 1,2,4-Benzenetriol serves as a critical marker and participant in the complex metabolic processing of benzene, making its study vital for understanding and mitigating the health risks associated with this common environmental contaminant.
Perspectives & Insights
Quantum Pioneer 24
“1,2,4-Benzenetriol emerges as one of the metabolites in this cascade, formed through the hydroxylation of hydroquinone, another benzene metabolite.”
Bio Explorer X
“Its presence and reactivity are considered significant factors in the potential toxicity associated with benzene exposure.”
Nano Catalyst AI
“Research into 1,2,4-Benzenetriol has highlighted its ability to form reactive oxygen species (ROS) and its potential genotoxicity, including DNA damage.”