Understanding the Chemical Profile of 1,2-Dibromobenzene (CAS 583-53-9)
NINGBO INNO PHARMCHEM CO.,LTD. is committed to empowering chemical professionals with comprehensive information about the compounds we supply. Today, we focus on 1,2-dibromobenzene (CAS 583-53-9), detailing its key chemical properties, safety aspects, and extensive applications in synthesis.
1,2-Dibromobenzene, also known as o-dibromobenzene, is an organobromine compound with the molecular formula C6H4Br2. It presents as a clear, colorless liquid with a distinct melting point of approximately -4 to -6 °C and a boiling point around 224 °C. Its density is significantly higher than water, at approximately 1.956 g/mL at 25 °C. These physical characteristics, along with its refractive index of n20/D 1.611, are important for handling and processing.
From a chemical reactivity standpoint, the 1,2-dibromobenzene chemical properties are defined by the presence of two bromine atoms on adjacent positions of the benzene ring. This structure makes it an excellent substrate for electrophilic aromatic substitution and, crucially, for organometallic reactions such as cross-couplings. Its utility as a precursor for benzyne intermediates further highlights its importance in complex organic synthesis. Understanding these uses of o-dibromobenzene in synthesis is vital for chemists aiming for efficient and precise molecular construction.
Safety is a paramount consideration when working with any chemical. While specific handling procedures should always be followed as per the Safety Data Sheet (SDS), general precautions for aromatic halides include working in well-ventilated areas and using appropriate personal protective equipment (PPE). For those looking to buy 1,2-dibromobenzene online, NINGBO INNO PHARMCHEM CO.,LTD. ensures that necessary safety information is readily available.
The compound's application as a pharmaceutical intermediate and its role in material science underscore its significance. Whether you require it for laboratory research or industrial production, securing a reliable supply with a competitive 1,2-dibromobenzene price per kg is essential. NINGBO INNO PHARMCHEM CO.,LTD. is your trusted partner for high-quality chemical sourcing.
Perspectives & Insights
Core Pioneer 24
“This structure makes it an excellent substrate for electrophilic aromatic substitution and, crucially, for organometallic reactions such as cross-couplings.”
Silicon Explorer X
“Its utility as a precursor for benzyne intermediates further highlights its importance in complex organic synthesis.”
Quantum Catalyst AI
“Understanding these uses of o-dibromobenzene in synthesis is vital for chemists aiming for efficient and precise molecular construction.”