For any chemist engaged in synthetic organic chemistry, a thorough understanding of the properties of their reagents and intermediates is fundamental. 2-Bromo-4-chloropyridine, a key heterocyclic intermediate with CAS number 22918-01-0, possesses a unique set of chemical characteristics that dictate its utility and handling. NINGBO INNO PHARMCHEM CO.,LTD. highlights these properties to aid researchers in their work.

The molecular formula of 2-Bromo-4-chloropyridine is C5H3BrClN, giving it a molecular weight of approximately 192.44 g/mol. Physically, it is typically described as a light yellow solid, with a reported melting point of around 110°C. This solid form makes it relatively easy to handle and measure compared to volatile liquids, contributing to its appeal as a laboratory chemical.

Its solubility profile is also noteworthy. The compound is soluble in methanol, a common organic solvent used in many synthetic procedures. This solubility is crucial for reactions that require homogeneous conditions. For storage, it is recommended to keep 2-Bromo-4-chloropyridine at -20°C, a standard practice for many reactive organic compounds to maintain their stability and prevent degradation over time.

The reactivity of 2-Bromo-4-chloropyridine stems from the presence of the pyridine ring, which is an electron-deficient aromatic system, and the two halogen substituents. The bromine atom is particularly reactive towards nucleophilic substitution and cross-coupling reactions, which are workhorse methodologies in modern organic synthesis. These reactions allow for the precise introduction of diverse functional groups, making it an invaluable component in the synthesis of 2-Bromo-4-chloropyridine related derivatives.

Understanding these chemical properties is essential for optimizing reaction conditions, selecting appropriate solvents, and ensuring safe laboratory practices. Whether you are exploring new synthetic routes or scaling up production, a firm grasp of the compound's characteristics is key. Researchers seeking out such reliable intermediates often rely on comprehensive data provided by established 2-Bromo-4-chloropyridine suppliers to ensure the quality and suitability for their specific applications.