Understanding the Chemical Properties of 3-Chloro-2-Fluorobenzoic Acid
A thorough understanding of a chemical compound's properties is fundamental to its effective application. 3-Chloro-2-fluorobenzoic acid (CAS 161957-55-7) possesses a unique set of physical and chemical characteristics that make it valuable in a wide range of synthetic processes.
Physically, it typically presents as a white to off-white powder or crystalline solid. Its melting point, generally falling within the range of 177-180°C, indicates a relatively stable solid form at room temperature. The reported boiling point, approximately 278.9°C, suggests stability under elevated temperatures, though decomposition might occur at higher points.
Chemically, the presence of both a chlorine and a fluorine atom on the aromatic ring, along with the carboxylic acid group, dictates its reactivity. The electron-withdrawing nature of the halogens influences the acidity of the carboxylic acid and the reactivity of the aromatic ring towards electrophilic or nucleophilic substitution. Its solubility in common organic solvents like methanol is also a key characteristic for its use in reactions and purifications.
Proper storage is essential to maintain its quality. Keeping the container sealed in a cool, dry, and well-ventilated warehouse, away from incompatible materials like oxidizing agents, is crucial. This ensures that the compound retains its purity and reactivity for intended applications.
NINGBO INNO PHARMCHEM CO.,LTD., as a responsible manufacturer and supplier, provides detailed specifications and ensures the quality of 3-Chloro-2-fluorobenzoic acid. Understanding these properties allows chemists and researchers to confidently incorporate this vital intermediate into their synthetic strategies, whether for pharmaceutical intermediate synthesis or as an agrochemical building block.
Physically, it typically presents as a white to off-white powder or crystalline solid. Its melting point, generally falling within the range of 177-180°C, indicates a relatively stable solid form at room temperature. The reported boiling point, approximately 278.9°C, suggests stability under elevated temperatures, though decomposition might occur at higher points.
Chemically, the presence of both a chlorine and a fluorine atom on the aromatic ring, along with the carboxylic acid group, dictates its reactivity. The electron-withdrawing nature of the halogens influences the acidity of the carboxylic acid and the reactivity of the aromatic ring towards electrophilic or nucleophilic substitution. Its solubility in common organic solvents like methanol is also a key characteristic for its use in reactions and purifications.
Proper storage is essential to maintain its quality. Keeping the container sealed in a cool, dry, and well-ventilated warehouse, away from incompatible materials like oxidizing agents, is crucial. This ensures that the compound retains its purity and reactivity for intended applications.
NINGBO INNO PHARMCHEM CO.,LTD., as a responsible manufacturer and supplier, provides detailed specifications and ensures the quality of 3-Chloro-2-fluorobenzoic acid. Understanding these properties allows chemists and researchers to confidently incorporate this vital intermediate into their synthetic strategies, whether for pharmaceutical intermediate synthesis or as an agrochemical building block.
Perspectives & Insights
Logic Thinker AI
“The electron-withdrawing nature of the halogens influences the acidity of the carboxylic acid and the reactivity of the aromatic ring towards electrophilic or nucleophilic substitution.”
Molecule Spark 2025
“Its solubility in common organic solvents like methanol is also a key characteristic for its use in reactions and purifications.”
Alpha Pioneer 01
“Keeping the container sealed in a cool, dry, and well-ventilated warehouse, away from incompatible materials like oxidizing agents, is crucial.”