For chemists, formulators, and researchers working with fine chemical intermediates, a deep understanding of a compound's properties is fundamental to its successful application. 4-Hydroxybenzotriazole (CAS 26725-51-9) is one such compound whose chemical characteristics dictate its utility in various synthetic and formulation processes.

Introduction to 4-Hydroxybenzotriazole

4-Hydroxybenzotriazole is a heterocyclic organic compound characterized by a benzotriazole ring fused with a hydroxyl group. Its presence in chemical catalogs, often listed under synonyms like 1H-1,2,3-Benzotriazol-4-ol, highlights its specific structure. As a key intermediate, understanding its physical and chemical properties is crucial for anyone looking to buy or utilize it effectively.

Physical Characteristics: Appearance and State

Typically, 4-Hydroxybenzotriazole is encountered as a solid. The visual appearance can range from light orange to a more pronounced orange hue, often in a powder or crystalline form. This physical state is important for handling, storage, and dispensing in laboratory or industrial settings. When procured from a reliable manufacturer, the consistency of its appearance is often an indicator of quality.

Key Chemical Properties

  • Melting Point: A significant physical property is its melting point, which is reported to be around 224°C, often with decomposition. This high melting point indicates a relatively stable crystalline structure at ambient temperatures, which is advantageous for storage and handling.
  • Solubility: Information regarding its solubility is vital for reaction design. Sources indicate it has slight solubility in DMSO and Methanol. This limited solubility in common organic solvents suggests that specific reaction conditions or co-solvents might be necessary for certain applications. Procurement managers should verify solubility data when considering bulk purchases for formulation.
  • Molecular Formula and Weight: The molecular formula of 4-Hydroxybenzotriazole is C6H5N3O, with a molecular weight of approximately 135.12 g/mol. These fundamental identifiers are essential for stoichiometric calculations in synthesis and for analytical purposes.
  • Reactivity: As a benzotriazole derivative with a hydroxyl group, 4-Hydroxybenzotriazole can exhibit characteristic reactivities. The hydroxyl group can participate in reactions such as esterification or etherification, while the benzotriazole moiety can influence its electronic properties and potential for chelation or other interactions. For R&D scientists, exploring its reactivity profile can unlock new synthetic possibilities.

Safety and Handling Considerations

Information regarding safety is always critical. Hazard codes (e.g., Xn, Xi) and risk statements (e.g., H302-H312-H315-H319-H332-H335) indicate that it can be harmful if swallowed, inhaled, or in contact with skin, and may cause skin, eye, and respiratory irritation. Precautionary statements (e.g., P280a, P305+P351+P338) provide guidance on protective measures. A comprehensive Safety Data Sheet (SDS) from the manufacturer is essential for safe handling and storage.

Sourcing High-Quality 4-Hydroxybenzotriazole

When you buy 4-Hydroxybenzotriazole, ensure your supplier provides detailed technical specifications that align with these properties. As a manufacturer and supplier, we are committed to providing products that meet high standards of purity and are accompanied by comprehensive technical documentation. Understanding these chemical properties will empower researchers and procurement professionals to make informed decisions and optimize their use of this versatile intermediate.

Conclusion

The chemical properties of 4-Hydroxybenzotriazole are key to its successful application. By understanding its appearance, melting point, solubility, and reactivity, scientists and procurement managers can better select and utilize this important fine chemical intermediate. Reliable suppliers, like us, ensure that you receive material with well-defined characteristics, facilitating your research and production goals.