Understanding Malononitrile (CAS 109-77-3): Properties, Synthesis, and Applications
Malononitrile, a chemical compound identified by CAS number 109-77-3, is a cornerstone in modern chemical industries, prized for its versatility as an intermediate. Also known by synonyms like Propanedinitrile, Malonodinitrile, and Dicyanomethane, this compound plays a crucial role in synthesizing a wide range of products across pharmaceuticals, agrochemicals, and dye manufacturing.
Chemically, Malononitrile is characterized by its high reactivity, stemming from the presence of two electron-withdrawing cyano groups attached to a methylene carbon. This structure allows it to readily participate in various nucleophilic addition and condensation reactions, making it an ideal building block for complex organic molecules. Typically appearing as a colorless crystalline solid, it possesses a melting point between 30-32°C, a key physical property for its handling and use.
The synthesis of Malononitrile can be achieved through several industrial methods, including the dehydration of cyanoacetamide or gas-phase reactions involving acetonitrile and cyanogen chloride. These processes are optimized for scalability and efficiency, ensuring a steady supply of this critical intermediate.
Its applications are notably diverse. In the pharmaceutical sector, Malononitrile is fundamental for producing various drugs, including diuretics, vitamin B1, and chemotherapy agents like methotrexate. In agriculture, it is a key precursor for synthesizing widely used herbicides such as bensulfuron-methyl and pyrisulfuron-methyl, contributing to efficient weed control.
The dye industry utilizes Malononitrile to enhance color stability and properties in photographic dyes and synthetic fibers. Its utility also extends to niche applications like additives in lubricants and as an extractant for precious metals.
For businesses in need of this essential chemical intermediate, sourcing from reputable manufacturers in China offers access to high-purity Malononitrile at competitive prices. Understanding its properties and applications allows for its effective integration into various production workflows. Whether for pharmaceutical synthesis, agrochemical development, or dye formulation, Malononitrile (CAS 109-77-3) remains a vital chemical intermediate with enduring significance.
Procuring this compound from trusted suppliers ensures the quality and consistency required for demanding industrial processes, supporting innovation and product development across multiple sectors.
Chemically, Malononitrile is characterized by its high reactivity, stemming from the presence of two electron-withdrawing cyano groups attached to a methylene carbon. This structure allows it to readily participate in various nucleophilic addition and condensation reactions, making it an ideal building block for complex organic molecules. Typically appearing as a colorless crystalline solid, it possesses a melting point between 30-32°C, a key physical property for its handling and use.
The synthesis of Malononitrile can be achieved through several industrial methods, including the dehydration of cyanoacetamide or gas-phase reactions involving acetonitrile and cyanogen chloride. These processes are optimized for scalability and efficiency, ensuring a steady supply of this critical intermediate.
Its applications are notably diverse. In the pharmaceutical sector, Malononitrile is fundamental for producing various drugs, including diuretics, vitamin B1, and chemotherapy agents like methotrexate. In agriculture, it is a key precursor for synthesizing widely used herbicides such as bensulfuron-methyl and pyrisulfuron-methyl, contributing to efficient weed control.
The dye industry utilizes Malononitrile to enhance color stability and properties in photographic dyes and synthetic fibers. Its utility also extends to niche applications like additives in lubricants and as an extractant for precious metals.
For businesses in need of this essential chemical intermediate, sourcing from reputable manufacturers in China offers access to high-purity Malononitrile at competitive prices. Understanding its properties and applications allows for its effective integration into various production workflows. Whether for pharmaceutical synthesis, agrochemical development, or dye formulation, Malononitrile (CAS 109-77-3) remains a vital chemical intermediate with enduring significance.
Procuring this compound from trusted suppliers ensures the quality and consistency required for demanding industrial processes, supporting innovation and product development across multiple sectors.
Perspectives & Insights
Alpha Spark Labs
“For businesses in need of this essential chemical intermediate, sourcing from reputable manufacturers in China offers access to high-purity Malononitrile at competitive prices.”
Future Pioneer 88
“Understanding its properties and applications allows for its effective integration into various production workflows.”
Core Explorer Pro
“Whether for pharmaceutical synthesis, agrochemical development, or dye formulation, Malononitrile (CAS 109-77-3) remains a vital chemical intermediate with enduring significance.”