For professionals engaged in chemical research, development, and manufacturing, a thorough understanding of key chemical intermediates is fundamental. Methyl Thioglycolate (CAS 2365-48-2), also known by synonyms such as Methyl 2-mercaptoacetate or Thioglycolic acid methyl ester, is a compound of significant interest due to its unique chemical properties and diverse applications. This article provides an in-depth look at its characteristics and synthesis, aimed at assisting chemists and procurement specialists in making informed decisions when they intend to buy Methyl Thioglycolate.

Key Physical and Chemical Properties:

Methyl Thioglycolate is typically described as a clear, colorless to pale green liquid. It possesses a distinct, often described as strong and unpleasant, garlic-like odor. The compound has a molecular formula of C3H6O2S and a molecular weight of approximately 106.15 g/mol. Its boiling point is around 42-43 °C at 10 mmHg, with a density of about 1.187 g/mL at 25 °C. Its solubility in water is moderate, approximately 40 g/L at 20 °C.

Chemically, the presence of both a thiol (-SH) group and an ester (-COOCH3) group imparts significant reactivity to Methyl Thioglycolate. The thiol group makes it a potent nucleophile and capable of undergoing oxidation and alkylation reactions. The ester group can participate in hydrolysis and transesterification reactions.

Synthesis Methods:

The industrial synthesis of Methyl Thioglycolate commonly involves the esterification of thioglycolic acid with methanol. A typical process might include reacting thioglycolic acid with methanol in a specific molar ratio, often in the presence of an acid catalyst such as p-toluenesulfonic acid. The reaction mixture is then heated to facilitate the esterification. Following the reaction, purification, often through distillation, is performed to isolate the high-purity Methyl Thioglycolate. The efficiency and yield of this process are critical for ensuring a cost-effective supply chain, which is why partnering with a capable Methyl Thioglycolate manufacturer is crucial.

The compound's versatility extends to its use as a model system for studying oxidative DNA damage, and its role in neocarzinostatin activation highlights its biochemical relevance. For those looking to procure this essential chemical, understanding these properties is key to identifying the right Acetic acid, 2-mercapto-, methyl ester supplier.

As a professional chemical supplier, we offer Methyl Thioglycolate that meets rigorous quality standards. We are equipped to handle inquiries for various quantities, from laboratory-scale research needs to industrial bulk purchases. Engaging with us means accessing not only a reliable source for Methyl 2-mercaptoacetate but also expert support regarding its properties and applications.