Methyllithium (CAS 917-54-4) is a critical organometallic reagent widely employed in organic synthesis due to its potent reactivity. Understanding its fundamental properties, diverse applications, and reliable sourcing channels is essential for chemists and procurement specialists. This guide provides a foundational overview for anyone looking to buy Methyllithium for their research or production needs.

The compound, with the chemical formula CH3Li and a molecular weight of 21.98, typically presents as a colorless transparent liquid. Its high purity, often specified at 99%, is a hallmark of quality, ensuring predictable and efficient reaction outcomes. Methyllithium's significance in chemistry stems from its dual role: it acts as a powerful organic base capable of deprotonating a wide range of substrates, and as an effective methylating agent, transferring a methyl group to electrophilic sites.

Its utility as a base is crucial in many synthetic pathways, facilitating the generation of reactive intermediates like carbanions, which are fundamental for building complex carbon skeletons. These reactions often involve the formation of new carbon-carbon bonds, a cornerstone of organic synthesis. As a methylating agent, Methyllithium enables the direct introduction of methyl groups, a common modification that can significantly alter a molecule's physical, chemical, and biological properties. This is particularly important in the pharmaceutical industry for synthesizing drug candidates and intermediates.

When considering the purchase of Methyllithium, prospective buyers should look for manufacturers committed to quality and consistency. NINGBO INNO PHARMCHEM CO.,LTD. is positioned as a key supplier, offering high-purity CH3Li. Buyers should also inquire about the typical forms it is supplied in, such as solutions in diethyl ether at specific molar concentrations (e.g., 1.6M), and ensure these meet their experimental requirements. Establishing a relationship with a trusted supplier can also provide competitive pricing and ensure a stable supply chain, which is vital for ongoing research or manufacturing operations.

In summary, Methyllithium is a cornerstone reagent in modern organic chemistry. By understanding its properties, applications, and the importance of sourcing from reputable manufacturers like NINGBO INNO PHARMCHEM CO.,LTD., chemists can confidently integrate this vital compound into their synthetic strategies to achieve precise and efficient chemical transformations.