Understanding Poloxamer 188: A Key Excipient in Modern Pharmaceuticals
NINGBO INNO PHARMCHEM CO.,LTD. is proud to discuss the vital role of Poloxamer 188 in the pharmaceutical industry. As a leading supplier, we understand the importance of high-purity chemical ingredients for the efficacy and safety of drug products. Poloxamer 188, a non-ionic surfactant with the CAS number 9003-11-6, has emerged as a cornerstone excipient due to its remarkable properties and versatility.
Poloxamer 188, also known by its chemical name Polyethylene-polypropylene glycol, is a triblock copolymer. Its unique structure, featuring a hydrophobic polyoxypropylene core flanked by two hydrophilic polyoxyethylene chains, grants it exceptional surface-active properties. This molecular architecture allows Poloxamer 188 to function effectively as an emulsifier, solubilizing agent, and stabilizer in a wide range of pharmaceutical formulations. Its minimal toxicity and low irritation potential make it particularly suitable for applications involving direct contact with biological tissues, such as in ointments, suppositories, and even advanced medical applications like artificial tears.
One of the most significant contributions of Poloxamer 188 to pharmaceutical science is its role in drug delivery systems. The surfactant's ability to form micelles and stabilize lipid-based formulations can enhance the solubility and bioavailability of poorly water-soluble drugs. This means that the active pharmaceutical ingredients (APIs) can be more effectively absorbed by the body, leading to improved therapeutic outcomes. Pharmaceutical companies worldwide rely on sourcing high-purity Poloxamer 188 to ensure the consistent performance and safety of their drug products. The purchase of Poloxamer 188 from reputable suppliers like NINGBO INNO PHARMCHEM CO.,LTD. guarantees adherence to stringent quality standards, essential for regulatory compliance and patient well-being.
Furthermore, the utility of Poloxamer 188 extends beyond traditional drug formulations. In the realm of biopharmaceuticals, it is employed to protect sensitive cell lines and proteins during processing. Its ability to stabilize cell membranes from mechanical stress, a common issue in large-scale cell cultures and bioprocessing, is highly valued. This protective function helps maintain cell viability and integrity, which is critical for the production of therapeutic proteins, vaccines, and antibodies. The buy Poloxamer 188 decision for these advanced applications is driven by the need for reliable and gentle handling of biological materials.
NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing pharmaceutical manufacturers with access to high-grade Poloxamer 188, ensuring that your drug development and production processes are supported by ingredients of the highest quality. We understand that the price and consistent supply of key raw materials like Poloxamer 188 are crucial for the success of your ventures. By choosing us as your supplier, you are investing in quality, reliability, and a partnership focused on advancing pharmaceutical innovation.
Perspectives & Insights
Logic Thinker AI
“is proud to discuss the vital role of Poloxamer 188 in the pharmaceutical industry.”
Molecule Spark 2025
“As a leading supplier, we understand the importance of high-purity chemical ingredients for the efficacy and safety of drug products.”
Alpha Pioneer 01
“Poloxamer 188, a non-ionic surfactant with the CAS number 9003-11-6, has emerged as a cornerstone excipient due to its remarkable properties and versatility.”