In the realm of specialized chemical intermediates, a thorough understanding of a compound's properties and handling requirements is paramount for successful and safe utilization. 2-Bromo-5-fluorobenzyl bromide, identified by its CAS number 112399-50-5, is a compound that demands such attention. As a critical building block in organic synthesis, particularly for pharmaceutical and agrochemical development, its physical and chemical characteristics dictate its application and storage protocols. Sourcing this material from a reputable manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. ensures you receive detailed product specifications to guide your work.

Chemically, 2-Bromo-5-fluorobenzyl bromide possesses the molecular formula C7H5Br2F and a molecular weight of approximately 267.92 g/mol. Its structure features a benzyl bromide core substituted with both a bromine atom and a fluorine atom on the aromatic ring. This arrangement imbues it with specific reactivity, making it an effective alkylating agent. Physically, it is typically described as a white fused solid. Key physical properties often cited include a melting point in the range of 34-35°C and a boiling point around 89-90°C at reduced pressure (1mm). These properties suggest that it is a relatively stable solid at room temperature, with a moderate volatility. Its appearance as a white solid and a high purity level (often specified as ≥98.0% by GC) are indicative of its quality as an intermediate for precise chemical synthesis.

Handling 2-Bromo-5-fluorobenzyl bromide requires adherence to standard laboratory safety practices for reactive organic halides. As with many benzyl bromides, it can be a lachrymator (tear-inducing) and skin irritant, so it should be handled in a well-ventilated fume hood using appropriate personal protective equipment (PPE), including gloves, eye protection, and lab coats. Understanding its reactivity is also crucial; it readily undergoes nucleophilic substitution reactions. Therefore, it should be kept away from strong bases and nucleophiles unless intended for a reaction. Its potential for decomposition under certain conditions means that careful attention to storage is necessary.

Proper storage is vital to maintain the integrity and reactivity of 2-Bromo-5-fluorobenzyl bromide. Recommendations typically include storing the compound in a cool, dry, and well-ventilated place, away from sources of ignition and incompatible materials such as strong oxidizing agents. Many suppliers suggest refrigeration (e.g., 2-8°C) to ensure long-term stability. By following these guidelines, researchers and manufacturers can preserve the high purity and reactivity of this essential intermediate, ensuring its efficacy in demanding organic synthesis applications. When you decide to buy 2-Bromo-5-fluorobenzyl bromide, remember that quality and proper handling are key. NINGBO INNO PHARMCHEM CO.,LTD. provides reliable products and information to support your chemical research needs.