For scientists working with chemical compounds, a thorough understanding of their properties and appropriate handling procedures is crucial for ensuring successful experimental outcomes and maintaining laboratory safety. 3-[2-(Trifluoromethyl)phenyl]propanoic acid, designated by CAS number 94022-99-8, is a valuable organic intermediate that requires careful consideration of its characteristics. This article provides insights into its properties and best practices for handling.

Chemically, 3-[2-(Trifluoromethyl)phenyl]propanoic acid is an organic acid featuring a phenyl ring substituted with a trifluoromethyl group at the ortho position, attached to a propanoic acid chain. Its molecular formula is C10H9F3O2, with a molecular weight of approximately 218.17 g/mol. As reported by various chemical suppliers, its typical appearance is a white to off-white powder. Understanding its solubility is also important; it is generally soluble in polar organic solvents such as dimethyl sulfoxide (DMSO) and methanol, though potentially only slightly soluble in some instances, which can influence reaction conditions and purification strategies.

The melting point of 3-[2-(Trifluoromethyl)phenyl]propanoic acid is typically in the range of 84-88 °C, and its boiling point is around 266.9 °C at standard atmospheric pressure. These thermal properties are important for processes involving heating or distillation. The compound's density is approximately 1.307 g/cm3. Proper storage is key to maintaining its integrity. It is generally recommended to store it sealed in a dry environment at room temperature or under refrigeration (2-8°C), as specified by individual suppliers, to prevent degradation or contamination.

For researchers looking to buy 3-[2-(Trifluoromethyl)phenyl]propanoic acid, it is vital to source it from reputable suppliers who provide comprehensive product information, including a Certificate of Analysis (CoA). This document details the purity, identity, and any relevant analytical data for the specific batch. When working with this compound, standard laboratory safety practices should be followed, including the use of appropriate personal protective equipment (PPE) such as gloves, safety glasses, and lab coats.

The primary applications of 3-[2-(Trifluoromethyl)phenyl]propanoic acid lie in its use as a chemical intermediate, particularly in the synthesis of pharmaceuticals and other fine chemicals. Its trifluoromethylphenyl moiety makes it a valuable building block for creating molecules with tailored biological activities. Companies like NINGBO INNO PHARMCHEM CO.,LTD. provide this essential compound to support the ongoing work of chemists and researchers in advancing various fields of science.