For professionals in the chemical industry, a thorough understanding of a compound's properties is fundamental to its effective and safe utilization. 4-Iodophenylhydrazine, identified by its CAS number 13116-27-3, is a versatile chemical intermediate with specific characteristics that dictate its application and handling. This article delves into the key properties of 4-Iodophenylhydrazine, offering insights for chemists, researchers, and procurement managers working with this compound. We, as a dedicated manufacturer and supplier, ensure that our product meets high standards for your critical synthesis needs.

Physically, 4-Iodophenylhydrazine typically presents as a tan crystalline solid. Its melting point, usually in the range of 101-106 °C, indicates its solid state under standard laboratory conditions. While soluble in water is often listed as insoluble, its solubility in organic solvents can vary and is an important consideration for reaction design. A critical property to note is its light sensitivity; exposure to light can lead to degradation. Therefore, proper storage in dark conditions, often under an inert atmosphere, is crucial for maintaining its purity and reactivity over time. Many suppliers, including ourselves, recommend storing it in a cool environment, typically below -20°C, and ensuring the container remains tightly closed in a dry, well-ventilated area.

The chemical reactivity of 4-Iodophenylhydrazine stems from its functional groups. The hydrazine moiety (-NHNH2) is nucleophilic and can readily react with carbonyl compounds (aldehydes and ketones) to form hydrazones, a common reaction in organic synthesis. The iodine atom attached to the phenyl ring is an aryl halide, making it amenable to various palladium-catalyzed cross-coupling reactions, such as Suzuki, Heck, and Sonogashira couplings. These reactions are powerful tools for constructing carbon-carbon bonds and are widely used in the synthesis of pharmaceuticals, agrochemicals, and advanced materials.

Safety is a paramount concern when working with any chemical, and 4-Iodophenylhydrazine is no exception. It is classified as harmful if swallowed, causes skin irritation, serious eye irritation, and may cause respiratory irritation. Appropriate personal protective equipment (PPE) is essential, including chemical-resistant gloves, safety goggles or a face shield, and laboratory coats. When handling the powder, working in a well-ventilated area or under a fume hood is highly recommended to minimize inhalation risk. Always refer to the Safety Data Sheet (SDS) provided by the supplier for detailed hazard information and emergency procedures.

For businesses looking to purchase 4-Iodophenylhydrazine, understanding these properties and handling requirements is vital for seamless integration into their processes. As a manufacturer in China, we supply 4-Iodophenylhydrazine that adheres to purity specifications and comes with comprehensive safety information. We are committed to providing reliable materials and supporting our customers with the necessary technical data to ensure safe and effective use.

We encourage all users of 4-Iodophenylhydrazine to prioritize safety and proper storage to maintain product integrity. For your sourcing needs, consider us your trusted partner for quality chemicals. Contact us to inquire about purchasing 4-Iodophenylhydrazine and to receive the most up-to-date product and safety information.