For professionals in the chemical industry, a thorough understanding of a compound's properties is essential for its effective utilization. 4-Aminotrifluorotoluene, identified by CAS number 455-14-1 and commonly referred to as p-Aminobenzotrifluoride, is a chemical intermediate whose characteristics lend themselves to a wide array of synthetic applications. This article aims to elucidate the key properties of 4-Aminotrifluorotoluene and touch upon its synthesis considerations, providing valuable insights for researchers and manufacturers.

The physical state of 4-Aminotrifluorotoluene at room temperature is typically a clear, colorless to yellow liquid. Its melting point is relatively low, ranging from 3-8°C, which is consistent with its liquid form under standard laboratory conditions. The boiling point is recorded at approximately 190°C at atmospheric pressure, indicating its moderate volatility. These physical parameters are critical for handling, storage, and reaction design. The refractive index, around 1.478 to 1.483, and density, approximately 1.283 g/mL, are also important identifiers and are useful for quality control checks by suppliers and users alike.

Chemically, 4-Aminotrifluorotoluene is characterized by the presence of an amine (-NH2) group and a trifluoromethyl (-CF3) group on a benzene ring. The trifluoromethyl group is a strong electron-withdrawing substituent, which significantly influences the electron density of the aromatic ring and the basicity of the amine group. This makes the amine less basic compared to aniline, for example. Conversely, the trifluoromethyl group can activate the aromatic ring towards nucleophilic aromatic substitution under specific conditions, though electrophilic aromatic substitution will be directed and deactivated.

The synthesis of 4-Aminotrifluorotoluene often involves the reduction of 4-nitrobenzotrifluoride. Various reducing agents and conditions can be employed, and the choice of method depends on factors such as desired purity, yield, cost, and environmental considerations. For manufacturers, optimizing these synthesis routes is crucial to ensure product quality and cost-effectiveness. When you buy 4-Aminotrifluorotoluene CAS 455-14-1, you are procuring a product that has undergone careful manufacturing processes to meet specific quality standards, such as USP, BP, and FCC, when applicable.

The understanding of these properties is fundamental for anyone looking to integrate 4-Aminotrifluorotoluene into their work. Whether it's for trifluoromethylaniline synthesis applications in pharmaceuticals, agrochemicals, or fine chemicals, knowing how to handle and react this compound is key to success. NINGBO INNO PHARMCHEM CO.,LTD., as a leading p-Aminobenzotrifluoride supplier in China, provides detailed technical data sheets that complement this understanding, ensuring users have all the necessary information for safe and effective use.

In conclusion, 4-Aminotrifluorotoluene (CAS 455-14-1) is a compound with a well-defined set of physical and chemical properties that make it invaluable in modern synthesis. By appreciating these characteristics and ensuring a reliable supply from reputable sources like NINGBO INNO PHARMCHEM CO.,LTD., researchers and manufacturers can effectively leverage its potential in developing innovative chemical products.