Bromopentafluorobenzene, designated by CAS number 344-04-7, is a compelling organofluorine compound recognized for its distinct chemical properties and its utility as a reactive intermediate. Understanding these attributes is key for chemists and procurement specialists looking to leverage this molecule in their syntheses. This article explores its physical and chemical characteristics, along with common synthetic routes.

Physically, Bromopentafluorobenzene is described as a colorless liquid. Its molecular formula, C6BrF5, highlights the significant fluorine substitution on the phenyl ring, a feature that dictates much of its chemical behavior. Key physical properties, such as a boiling point of approximately 137°C and a melting point around -31°C, indicate it remains liquid under typical laboratory conditions. Its density is notably higher than water, around 1.98 g/mL, a common trait for highly halogenated organic compounds.

Chemically, the pentafluorophenyl group is strongly electron-withdrawing. This electronic effect profoundly influences the reactivity of the attached bromine atom, making it susceptible to nucleophilic displacement and enabling its use in forming organometallic reagents, such as Grignard reagents and organolithium compounds. These reagents are fundamental for building carbon-carbon bonds, a cornerstone of organic synthesis. For example, the synthesis of tris(pentafluorophenyl)borane is a well-known application derived from the Grignard reagent of Bromopentafluorobenzene.

The synthesis of Bromopentafluorobenzene typically involves the direct bromination of pentafluorobenzene. Various methods can be employed to achieve this transformation, often utilizing brominating agents in the presence of catalysts or under specific reaction conditions to ensure regioselectivity and high yield. Ensuring the purity of the starting materials and optimizing reaction parameters are critical for obtaining high-quality Bromopentafluorobenzene, making it essential to buy from a reliable manufacturer with robust synthesis capabilities.

For professionals in the pharmaceutical and specialty chemical sectors, accessing this compound is vital. Whether it's for developing new drug candidates or innovative materials, securing a dependable supplier of Bromopentafluorobenzene is crucial. Procurement managers often investigate the price and availability from various sources, with many choosing to partner with Chinese manufacturers due to their competitive production costs and expanding expertise in fine chemical synthesis.

In essence, the distinctive properties of Bromopentafluorobenzene (CAS 344-04-7), arising from its highly fluorinated structure, position it as a cornerstone intermediate. Its synthesis and reactivity are central to creating advanced organic molecules. To effectively utilize this compound, diligent sourcing from quality-assured manufacturers is recommended. NINGBO INNO PHARMCHEM CO.,LTD. is a prominent Pentafluorophenyl bromide supplier dedicated to meeting these demands.