In the vast field of organic chemistry, specific molecules serve as linchpins, enabling the creation of more complex and functional compounds. CAS numbers are unique identifiers that help researchers and procurement specialists pinpoint these crucial chemical entities. Today, we focus on CAS 884494-87-5, a compound known scientifically as 3-Bromo-5-Chloro-2-Fluoropyridine.

This halogenated pyridine derivative is not just another chemical; it is a highly strategic intermediate. Its molecular structure, C5H2BrClFN, is rich with reactive sites due to the presence of bromine, chlorine, and fluorine atoms strategically positioned on the pyridine ring. This unique arrangement makes it an exceptionally versatile building block for advanced organic synthesis, particularly in the pharmaceutical and agrochemical sectors.

The Chemical Significance of CAS 884494-87-5

The utility of 3-Bromo-5-Chloro-2-Fluoropyridine stems from the distinct reactivity imparted by each halogen and the pyridine core. The bromine atom, for instance, is an excellent leaving group, readily participating in palladium-catalyzed cross-coupling reactions like Suzuki, Sonogashira, or Heck couplings. These reactions are fundamental for forming new carbon-carbon bonds, a cornerstone of complex molecule construction. The chlorine atom also offers opportunities for substitution or coupling under specific conditions, while the fluorine atom can significantly influence the electronic properties and metabolic stability of the final molecule.

Furthermore, the electron-deficient nature of the pyridine ring itself can direct reactivity and influence the properties of synthesized compounds. This combination of features allows chemists to meticulously engineer molecules with desired biological activities or material properties.

Applications and Procurement Insights

As a premier manufacturer and supplier of this intermediate, we see its application primarily in two major fields:

  • Pharmaceutical Synthesis: CAS 884494-87-5 is a key precursor for numerous Active Pharmaceutical Ingredients (APIs). Its structural versatility allows for its incorporation into drug candidates targeting a wide range of therapeutic areas. Researchers looking to buy this intermediate for drug discovery often seek high purity (e.g., ≥98.0%) to ensure reliable experimental results.
  • Agrochemical Development: The compound also plays a vital role in the synthesis of modern pesticides, herbicides, and fungicides. Its halogenated pyridine structure can contribute to enhanced efficacy, environmental persistence control, and targeted action against pests or weeds.

When sourcing CAS 884494-87-5, it is crucial to partner with a supplier who can guarantee both purity and consistent availability. Direct manufacturers based in China, such as NINGBO INNO PHARMCHEM, often provide the best balance of quality and cost. By understanding the specific needs of organic synthesis, we ensure our product meets the rigorous demands of our clients. If you are looking to buy this essential intermediate, we encourage you to contact us for a quote and to learn more about our production capabilities and commitment to quality.