Understanding the Synthesis and Purity of 4-Hydroxy-4'-nitrobiphenyl (CAS: 3916-44-7)
The successful application of chemical intermediates hinges on both effective synthesis routes and stringent purity control. 4-Hydroxy-4'-nitrobiphenyl (CAS: 3916-44-7) is a prime example of such a compound, whose utility in pharmaceutical synthesis and dye manufacturing is directly tied to its quality and the methods used to produce it.
The synthesis of 4-Hydroxy-4'-nitrobiphenyl often involves coupling reactions, such as Suzuki or similar cross-coupling methodologies, utilizing precursors like a nitrophenyl halide and a hydroxyphenyl boronic acid derivative. These processes require careful control of reaction conditions, catalysts, and purification steps to achieve the desired high purity, typically verified by Gas Chromatography (GC) to be 98.0% or higher. The compound's physical form is usually a light yellow crystalline powder, with a melting point around 207°C, and its molecular formula is C12H9NO3.
Ensuring the purity of 4-Hydroxy-4'-nitrobiphenyl is critical, especially when it functions as a pharmaceutical intermediate. The presence of even trace impurities can significantly impact the safety and efficacy of the final drug product. Similarly, for dye synthesis, consistent purity guarantees predictable color intensity and performance characteristics.
As a key organic synthesis building block, researchers and manufacturers actively seek reliable sources for this compound. The availability of detailed technical data, including CAS number (3916-44-7), molecular weight (215.21 g/mol), and purity specifications, from suppliers is essential for project planning and execution.
NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing 4-Hydroxy-4'-nitrobiphenyl that meets the highest industry standards. We focus on robust synthesis processes and rigorous quality assurance to ensure our customers receive a product they can trust for their critical applications. Whether you need this compound for pharmaceutical development, dye production, or other advanced organic synthesis projects, we are your reliable partner for quality chemical intermediates.
The synthesis of 4-Hydroxy-4'-nitrobiphenyl often involves coupling reactions, such as Suzuki or similar cross-coupling methodologies, utilizing precursors like a nitrophenyl halide and a hydroxyphenyl boronic acid derivative. These processes require careful control of reaction conditions, catalysts, and purification steps to achieve the desired high purity, typically verified by Gas Chromatography (GC) to be 98.0% or higher. The compound's physical form is usually a light yellow crystalline powder, with a melting point around 207°C, and its molecular formula is C12H9NO3.
Ensuring the purity of 4-Hydroxy-4'-nitrobiphenyl is critical, especially when it functions as a pharmaceutical intermediate. The presence of even trace impurities can significantly impact the safety and efficacy of the final drug product. Similarly, for dye synthesis, consistent purity guarantees predictable color intensity and performance characteristics.
As a key organic synthesis building block, researchers and manufacturers actively seek reliable sources for this compound. The availability of detailed technical data, including CAS number (3916-44-7), molecular weight (215.21 g/mol), and purity specifications, from suppliers is essential for project planning and execution.
NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing 4-Hydroxy-4'-nitrobiphenyl that meets the highest industry standards. We focus on robust synthesis processes and rigorous quality assurance to ensure our customers receive a product they can trust for their critical applications. Whether you need this compound for pharmaceutical development, dye production, or other advanced organic synthesis projects, we are your reliable partner for quality chemical intermediates.
Perspectives & Insights
Agile Reader One
“4-Hydroxy-4'-nitrobiphenyl (CAS: 3916-44-7) is a prime example of such a compound, whose utility in pharmaceutical synthesis and dye manufacturing is directly tied to its quality and the methods used to produce it.”
Logic Vision Labs
“The synthesis of 4-Hydroxy-4'-nitrobiphenyl often involves coupling reactions, such as Suzuki or similar cross-coupling methodologies, utilizing precursors like a nitrophenyl halide and a hydroxyphenyl boronic acid derivative.”
Molecule Origin 88
“These processes require careful control of reaction conditions, catalysts, and purification steps to achieve the desired high purity, typically verified by Gas Chromatography (GC) to be 98.”