For chemists and researchers working with organic intermediates, a thorough understanding of synthesis routes and safe handling protocols is indispensable. 1-Bromo-6-chlorohexane (CAS: 6294-17-3) is a critical bifunctional molecule that requires careful consideration in both its preparation and use. As a prominent organic synthesis intermediate manufacturer, we aim to provide clarity on these aspects.

Synthesis Pathways for 1-Bromo-6-chlorohexane

Several methods exist for synthesizing 1-Bromo-6-chlorohexane. A common approach involves the selective halogenation of precursors like 1,6-hexanediol. For instance:

  • From 1,6-Hexanediol: This diol can be reacted sequentially with brominating agents (e.g., hydrobromic acid or phosphorus tribromide) and chlorinating agents (e.g., thionyl chloride) under controlled conditions. Specific reaction parameters, catalysts, and solvents are critical to achieving high yields and purity of the desired mixed haloalkane while minimizing the formation of dibromo- or dichloro-hexanes.
  • Other Routes: Alternative pathways might involve the radical halogenation of hexane derivatives or other functionalized six-carbon chains, although these often present challenges in selectivity.

The goal is always to produce a compound with high purity, typically ≥99.0%, which is why reliable suppliers focus on optimized manufacturing processes. If you need to buy 1-bromo-6-chlorohexane, understanding these synthesis principles helps appreciate the value of a high-quality product.

Safe Handling and Storage Recommendations

As with many halogenated organic compounds, 1-Bromo-6-chlorohexane requires careful handling:

  • Personal Protective Equipment (PPE): Always wear appropriate PPE, including chemical-resistant gloves (e.g., nitrile or neoprene), safety goggles or a face shield, and a lab coat. Work in a well-ventilated area, preferably a fume hood, to avoid inhalation of vapors.
  • Inhalation and Skin Contact: The compound may cause respiratory irritation and skin irritation. Avoid direct contact and inhalation of vapors. In case of contact, wash affected areas immediately with plenty of soap and water.
  • Storage: Store 1-Bromo-6-chlorohexane in a cool, dry, and well-ventilated place, away from incompatible materials such as strong oxidizing agents. Keep containers tightly sealed when not in use.
  • Disposal: Dispose of waste material in accordance with local, regional, and national regulations for hazardous chemical waste.

Our role as a leading organic synthesis intermediate supplier extends beyond manufacturing; we are committed to providing customers with the necessary information for safe and effective use. For detailed safety data sheets (SDS) or to inquire about purchasing cas 6294-17-3, please contact us. We offer this essential intermediate in reliable packaging, such as 200 kg drums, ensuring both quality and safety.