The foundation of successful chemical manufacturing and pharmaceutical development often rests on the availability of high-quality intermediates. 4,6-Dichloro-2-(methylsulfonyl)pyrimidine, known by its CAS number 4489-34-3, is a prime example of such a critical building block. Understanding its synthesis and properties is essential for chemists and manufacturers aiming for optimal results.

The synthesis of 4,6-Dichloro-2-(methylsulfonyl)pyrimidine typically begins with a precursor like 4,6-dichloro-2-methylsulfanylpyrimidine. Through controlled oxidation, often employing oxidizing agents such as meta-chloroperoxybenzoic acid (m-CPBA), the methylthio group is converted into the methylsulfonyl group. This process requires careful control of reaction conditions, including temperature and reaction time, to ensure high yields and purity of the final product. NINGBO INNO PHARMCHEM CO.,LTD., as a leading manufacturer and supplier in China, employs robust synthetic protocols to deliver this chemical intermediate with exceptional quality.


Physically, 4,6-Dichloro-2-(methylsulfonyl)pyrimidine is characterized as a white crystalline powder. Its melting point, typically in the range of 117-118°C, is a key indicator of its purity. The compound is generally soluble in common organic solvents, facilitating its use in various reaction media. Its molecular formula, C5H4Cl2N2O2S, and molecular weight of approximately 227.07 g/mol are fundamental pieces of information for chemists performing stoichiometric calculations. For those looking to purchase this compound, NINGBO INNO PHARMCHEM CO.,LTD. ensures that each batch meets stringent specifications.


The importance of this pyrimidine derivative extends across multiple industries, from pharmaceuticals to agrochemicals. Its strategic importance as a chemical intermediate means that reliable sourcing is paramount. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing this essential compound at competitive prices, supporting the diverse needs of the global scientific community. Whether for laboratory synthesis or industrial applications, NINGBO INNO PHARMCHEM CO.,LTD. is your trusted partner in China.