Understanding the Chemical Properties and Applications of 4-Fluoro-3-nitrotoluene (CAS 446-11-7)
At NINGBO INNO PHARMCHEM CO.,LTD., we are dedicated to providing comprehensive information about the chemicals we supply. Today, we focus on 4-Fluoro-3-nitrotoluene, known by its CAS number 446-11-7, a compound of significant interest in the fine chemicals industry. This article aims to elucidate its key chemical properties and highlight its broad range of applications, emphasizing why it is a sought-after chemical intermediate.
The compound, also referred to as 1-fluoro-4-methyl-2-nitrobenzene, has a molecular formula of C7H6FNO2 and a molecular weight of 155.13. From a physical standpoint, it presents as a striking red-brown liquid. Its melting point typically falls between 27-29°C, and it boils at approximately 241°C. The density is recorded at 1.262, with a refractive index of 1.524. These precise CAS 446-11-7 chemical properties are crucial for chemists and process engineers when designing synthesis routes and ensuring proper handling and storage conditions. The product is often supplied with a minimum purity specification of 99% (GC), which is vital for demanding applications.
The versatility of 4-Fluoro-3-nitrotoluene as a pharmaceutical intermediate is a major driver of its demand. The strategic placement of the fluorine atom can significantly influence the pharmacokinetic and pharmacodynamic properties of drug molecules, leading to improved efficacy and reduced side effects. Similarly, in the agrochemical sector, its role as an agrochemical synthesis precursor is equally important. The incorporation of fluorinated moieties often leads to increased potency and stability of pesticides and herbicides, contributing to more effective crop protection. Companies looking to buy 4-fluoro-3-nitrotoluene purity can rely on its consistent quality for their critical manufacturing processes.
The compound's reactivity also makes it a valuable fine chemical synthesis raw material. The nitro group can be readily reduced to an amino group, opening up pathways for amide formation, diazotization, and other critical transformations. This dual reactivity, stemming from both the fluoro and nitro substituents, allows for diverse synthetic strategies. Understanding the full scope of 1-fluoro-4-methyl-2-nitrobenzene applications is key for researchers exploring new molecular entities. NINGBO INNO PHARMCHEM CO.,LTD. ensures that this essential 4-fluoro-3-nitrotoluene synthesis intermediate is available to support innovation across the chemical landscape.
Perspectives & Insights
Core Pioneer 24
“The versatility of 4-Fluoro-3-nitrotoluene as a pharmaceutical intermediate is a major driver of its demand.”
Silicon Explorer X
“The strategic placement of the fluorine atom can significantly influence the pharmacokinetic and pharmacodynamic properties of drug molecules, leading to improved efficacy and reduced side effects.”
Quantum Catalyst AI
“Similarly, in the agrochemical sector, its role as an agrochemical synthesis precursor is equally important.”