Methyl 2-iodobenzoate (CAS 610-97-9) is a chemical compound that demands a thorough understanding of its properties and synthesis for effective utilization. As a pivotal fine chemical intermediate, its physical and chemical characteristics dictate its suitability for various industrial applications. This article explores these critical aspects, providing insights for researchers and manufacturers.

The physical appearance of Methyl 2-iodobenzoate is typically described as a white to pale yellow crystalline powder or flaky solid. It has a melting point of approximately 64°C, indicating its solid state at standard room temperatures. Its solubility profile shows it is insoluble in water but soluble in common organic solvents such as chloroform, ethyl acetate, and methanol, which is a common trait for many organic esters. This solubility is a key factor when considering reaction media and purification techniques in its methyl 2-iodobenzoate synthesis.

The synthesis of Methyl 2-iodobenzoate often involves the esterification of 2-iodobenzoic acid. A common method involves reacting 2-iodobenzoic acid with methanol in the presence of an acid catalyst, such as sulfuric acid, and heating the mixture under reflux conditions. Following the reaction, standard work-up procedures, including extraction and evaporation, yield the desired product. The efficiency of the preparation of iodosobenzoate derivatives is directly linked to the purity and consistency of the starting Methyl 2-iodobenzoate.

Handling Methyl 2-iodobenzoate requires attention to its light-sensitive nature. It is recommended to store it in a dark place and in a dry, sealed container at room temperature to maintain its stability and purity. Incompatible with strong oxidizing agents, proper segregation during storage and handling is crucial. These considerations are vital for ensuring product integrity, especially when used as a pharmaceutical intermediate, where strict quality control is maintained throughout the supply chain.

Reliable sourcing is paramount for any chemist or manufacturer working with this compound. Companies like NINGBO INNO PHARMCHEM CO.,LTD. are known for providing high-purity Methyl 2-iodobenzoate. Understanding the methyl 2-iodobenzoate price and availability from various suppliers of methyl 2-iodobenzoate can inform procurement strategies. The emphasis on green chemistry in production is also becoming increasingly relevant, encouraging the adoption of sustainable synthesis methods.

In summary, a comprehensive understanding of Methyl 2-iodobenzoate's chemical properties, synthesis methods, and handling requirements is essential. As a crucial building block, its consistent quality and availability, often facilitated by specialized suppliers like NINGBO INNO PHARMCHEM CO.,LTD., underpin its widespread use in organic synthesis, pharmaceuticals, and beyond.