Understanding the Properties and Applications of 1-Hexanesulfonic Acid Sodium Salt Hydrate
The pursuit of accurate and reproducible results in scientific research often hinges on the quality of the chemical reagents employed. 1-Hexanesulfonic acid sodium salt hydrate (CAS 207300-91-2) is one such compound that has garnered significant attention in the scientific community due to its unique chemical characteristics and broad applicability, especially in analytical chemistry.
At its core, 1-Hexanesulfonic acid sodium salt hydrate is an amphiphilic molecule, meaning it possesses both water-soluble (hydrophilic) and oil-soluble (hydrophobic) components. This duality is primarily derived from its ionic sulfonate group and the aliphatic hexane chain, respectively. This structural feature makes it an excellent candidate for use as a surfactant or emulsifier, but its most prominent application is as an ion-pairing reagent in High-Performance Liquid Chromatography (HPLC).
In HPLC, ion-pairing agents are used to alter the retention behavior of ionic analytes on a reversed-phase column. 1-Hexanesulfonic acid sodium salt hydrate achieves this by forming an electrically neutral ion pair with charged analytes. The hydrophobic hexane chain then enhances the retention of this ion pair on the non-polar stationary phase. This technique is crucial for the successful separation of a wide range of compounds that would otherwise exhibit poor retention or peak shape. The diverse uses of 1-Hexanesulfonic acid sodium salt hydrate are testament to its effectiveness in these analytical challenges.
For professionals in the field, securing a reliable source to buy 1-Hexanesulfonic acid sodium salt hydrate is a key operational consideration. Many opt for high-purity grades, such as 1-Hexanesulfonic acid sodium salt hydrate HPLC grade, to ensure the integrity of their experimental results. Manufacturers in China, including Ningbo Inno Pharmchem Co., Ltd., are prominent suppliers known for their quality control and ability to meet the demands of international markets for fine chemicals.
The advantages of using this compound in analytical workflows are manifold: it allows for the analysis of polar and ionic compounds, improves peak symmetry, and increases sensitivity. These benefits are critical in industries such as pharmaceuticals, where accurate quantification of drug substances and impurities is essential, and in environmental science, for monitoring trace contaminants.
In summary, 1-Hexanesulfonic acid sodium salt hydrate is an indispensable reagent for modern analytical laboratories. Its amphiphilic nature and effectiveness as an ion-pairing agent make it a versatile tool for chromatography and other separation sciences, reinforcing the need for high-quality sourcing from reputable suppliers.
At its core, 1-Hexanesulfonic acid sodium salt hydrate is an amphiphilic molecule, meaning it possesses both water-soluble (hydrophilic) and oil-soluble (hydrophobic) components. This duality is primarily derived from its ionic sulfonate group and the aliphatic hexane chain, respectively. This structural feature makes it an excellent candidate for use as a surfactant or emulsifier, but its most prominent application is as an ion-pairing reagent in High-Performance Liquid Chromatography (HPLC).
In HPLC, ion-pairing agents are used to alter the retention behavior of ionic analytes on a reversed-phase column. 1-Hexanesulfonic acid sodium salt hydrate achieves this by forming an electrically neutral ion pair with charged analytes. The hydrophobic hexane chain then enhances the retention of this ion pair on the non-polar stationary phase. This technique is crucial for the successful separation of a wide range of compounds that would otherwise exhibit poor retention or peak shape. The diverse uses of 1-Hexanesulfonic acid sodium salt hydrate are testament to its effectiveness in these analytical challenges.
For professionals in the field, securing a reliable source to buy 1-Hexanesulfonic acid sodium salt hydrate is a key operational consideration. Many opt for high-purity grades, such as 1-Hexanesulfonic acid sodium salt hydrate HPLC grade, to ensure the integrity of their experimental results. Manufacturers in China, including Ningbo Inno Pharmchem Co., Ltd., are prominent suppliers known for their quality control and ability to meet the demands of international markets for fine chemicals.
The advantages of using this compound in analytical workflows are manifold: it allows for the analysis of polar and ionic compounds, improves peak symmetry, and increases sensitivity. These benefits are critical in industries such as pharmaceuticals, where accurate quantification of drug substances and impurities is essential, and in environmental science, for monitoring trace contaminants.
In summary, 1-Hexanesulfonic acid sodium salt hydrate is an indispensable reagent for modern analytical laboratories. Its amphiphilic nature and effectiveness as an ion-pairing agent make it a versatile tool for chromatography and other separation sciences, reinforcing the need for high-quality sourcing from reputable suppliers.
Perspectives & Insights
Data Seeker X
“Many opt for high-purity grades, such as 1-Hexanesulfonic acid sodium salt hydrate HPLC grade, to ensure the integrity of their experimental results.”
Chem Reader AI
“, are prominent suppliers known for their quality control and ability to meet the demands of international markets for fine chemicals.”
Agile Vision 2025
“The advantages of using this compound in analytical workflows are manifold: it allows for the analysis of polar and ionic compounds, improves peak symmetry, and increases sensitivity.”