2,2-Difluoroethanol (CAS 359-13-7) is a significant compound in the field of organic chemistry, valued for its unique properties and its extensive utility as an organic intermediate. This colorless liquid, characterized by its two fluorine atoms attached to the beta-carbon of an ethanol molecule, offers a distinct set of physical and chemical attributes that make it indispensable in various industrial processes.

Physically, 2,2-Difluoroethanol typically presents as a colorless liquid with a boiling point of approximately 95.5°C at standard atmospheric pressure. Its melting point is considerably lower, around -28°C, indicating its liquid state over a broad temperature range suitable for many chemical reactions. The compound also has a density of around 1.296 g/cm³, and it is generally soluble in water, ethanol, and chloroform. A key characteristic is its flammability, with a low flash point, necessitating careful handling and storage in well-ventilated, cool environments away from ignition sources.

Chemically, the presence of the two fluorine atoms significantly influences the molecule's properties. Fluorine is highly electronegative, and its proximity to the hydroxyl group in 2,2-Difluoroethanol increases the acidity of the hydroxyl proton compared to simple ethanol. This can affect its reactivity in certain reactions and its ability to participate in hydrogen bonding. These characteristics make it a valuable component in syntheses where precise control over electronic and steric factors is required.

The primary application of 2,2-Difluoroethanol lies in its role as a versatile organic intermediate. Its structure allows for the introduction of the difluoroethyl group into larger molecules, a modification frequently sought after in the development of pharmaceuticals and agrochemicals. In drug discovery, fluorination can enhance a compound's metabolic stability, lipophilicity, and target binding affinity, leading to more effective therapeutic agents. For instance, it can be used to synthesize compounds that improve drug delivery or prolong their duration of action. For those looking to buy 2,2-difluoroethanol for these purposes, sourcing from a reliable manufacturer is crucial.

In the agrochemical sector, 2,2-Difluoroethanol contributes to the creation of advanced pesticides and herbicides. The fluorine atoms can enhance the potency and selectivity of these agents, leading to more efficient crop protection. Its role as a key building block in these formulations highlights the importance of having consistent access to this chemical.

Companies interested in acquiring 2,2-Difluoroethanol should look for reputable suppliers, often found in regions like China, known for their robust chemical manufacturing capabilities. A dependable CAS 359-13-7 supplier will provide material with assured purity and timely delivery, facilitating uninterrupted research and production. When inquiring about 2,2-Difluoroethanol price, it's important to consider the overall value proposition, including quality, consistency, and technical support.

In summary, 2,2-Difluoroethanol is a compound of significant industrial value, driven by its unique physical and chemical properties and its critical role as an organic intermediate. Its applications in pharmaceuticals, agrochemicals, and beyond underscore the need for reliable sourcing from qualified manufacturers and suppliers.