In the realm of fine chemicals, understanding the nuances of each compound is critical for successful application. 4-Chlorobenzoyl Chloride (CAS 122-01-0) is a prime example of a chemical that requires specific knowledge regarding its properties, synthesis, and handling to maximize its utility. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing this essential information, ensuring our clients can effectively integrate this versatile intermediate into their processes.

The physical characteristics of 4-Chlorobenzoyl Chloride are well-defined. It typically appears as a clear, colorless to faintly colored liquid. Its melting point range is generally between 11-14 °C, and it boils around 102-104 °C at 11 mmHg. These properties are crucial for storage and processing considerations. As an acyl chloride, its chemical reactivity is its most defining feature. It readily participates in reactions with nucleophiles, which makes it invaluable for synthesis but also necessitates careful handling. The moisture sensitivity of 4-Chlorobenzoyl Chloride is a key consideration; exposure to water can lead to hydrolysis, producing 4-chlorobenzoic acid and hydrochloric acid. Therefore, maintaining a dry environment and tightly sealed containers is essential.

The synthesis of 4-Chlorobenzoyl Chloride is typically accomplished through the chlorination of 4-Chlorobenzoic acid, commonly using thionyl chloride. This reaction is a standard method in organic chemistry for converting carboxylic acids into their corresponding acyl chlorides. The efficiency and yield of this synthesis depend on controlled conditions, including temperature and the purity of the reactants. For manufacturers and researchers looking to purchase 4-Chlorobenzoyl Chloride, understanding the synthesis route can offer insights into potential impurities and the overall quality of the product. NINGBO INNO PHARMCHEM CO.,LTD. ensures stringent quality control throughout our production processes.

The applications of 4-Chlorobenzoyl Chloride are diverse, ranging from its use as a promoter in the synthesis of alpha-aminonitriles—critical intermediates for pharmaceuticals—to its function as a derivatization agent in analytical chemistry. It also plays a role in material science by improving hole injection in conjugated polymers. Each of these applications leverages the specific reactivity of the acyl chloride group. When considering its purchase, clients often inquire about the '4-Chlorobenzoyl Chloride price' and its availability, underscoring the demand for this versatile compound. NINGBO INNO PHARMCHEM CO.,LTD. aims to provide competitive pricing and reliable supply chains.

Safe handling of 4-Chlorobenzoyl Chloride is paramount due to its corrosive nature and reactivity. It is classified as a hazardous substance, with appropriate safety statements including protection against skin burns and eye damage. When working with this chemical, it is imperative to use appropriate personal protective equipment (PPE), such as gloves, eye protection, and lab coats, and to work in a well-ventilated area, preferably a fume hood. Storage recommendations typically include keeping the container tightly closed in a dry, well-ventilated place, away from incompatible materials like water, alcohols, bases, and strong oxidizing agents. Proper disposal procedures must also be followed according to local regulations.

In conclusion, 4-Chlorobenzoyl Chloride is an indispensable chemical intermediate whose effective use hinges on a thorough understanding of its properties and safe handling protocols. NINGBO INNO PHARMCHEM CO.,LTD. is committed to supporting our clients with high-quality products and comprehensive technical information, ensuring that this valuable compound can be utilized to its full potential in various chemical synthesis and research endeavors.