1-Chlorotetradecane, identified by CAS number 2425-54-9, is a vital chemical intermediate that plays a significant role in various industrial applications. This chlorinated alkane, also known by synonyms like tetradecyl chloride or myristyl chloride, possesses a unique set of physical and chemical properties that make it highly valuable in synthesis and manufacturing processes. Understanding these characteristics is key for any entity involved in its production or utilization.

Physically, 1-Chlorotetradecane presents as a colorless to pale yellow liquid. Its molecular formula, C14H29Cl, and a molecular weight of approximately 232.83 g/mol, are fundamental identifiers. A critical property is its boiling point, around 292.9°C at 760 mmHg, indicating its thermal stability. Conversely, it has a melting point of -3°C, meaning it remains a liquid under common ambient conditions. The compound exhibits a density of about 0.86 g/cm³, making it less dense than water. Its flash point is recorded at 122.5°C, signifying a moderate flammability risk that necessitates appropriate safety protocols during handling and storage.

From a chemical standpoint, 1-Chlorotetradecane is characterized by its low water solubility (< 0.01 g/L at 20°C), which points to its significant hydrophobic nature. This characteristic is crucial for its applications, particularly in forming nonionic microemulsions or when used in reactions that are sensitive to water. Its reactivity stems from the presence of the chlorine atom, which can participate in various substitution reactions, making it an excellent starting material for introducing a C14 alkyl chain into other molecules.

The synthesis of 1-Chlorotetradecane typically involves the chlorination of tetradecane or the conversion of 1-tetradecanol. Common industrial methods include the reaction of the corresponding alcohol with hydrogen chloride, often in the presence of a catalyst like zinc chloride, or via reactions involving thionyl chloride. For example, the reaction of 1-tetradecanol with hydrogen chloride gas at elevated temperatures, sometimes with catalysts, can yield high conversion rates. Industrial production often employs specialized reactors and distillation techniques to ensure product purity and efficient water removal during the process. Companies like NINGBO INNO PHARMCHEM CO.,LTD. focus on optimizing these synthesis routes to achieve high purity levels, often exceeding 98% or 99% as required by specific applications.

The primary uses of 1-Chlorotetradecane leverage these properties. It is widely recognized as an intermediate for surfactant manufacturing, contributing to the production of compounds like dimethyldimyristyl ammonium chloride. In the pharmaceutical industry, it serves as a valuable pharmaceutical intermediate for synthesizing complex molecules. Its role as a chemical synthesis building block extends to the creation of specialty chemicals, lubricants, and materials for research and development. The consistent quality and predictable reactivity of 1-Chlorotetradecane make it a reliable choice for demanding applications.

In conclusion, a thorough understanding of 1-Chlorotetradecane's physical and chemical properties, alongside its synthesis pathways, is essential for its effective utilization. As a versatile intermediate, it continues to be a key component in advancing chemical manufacturing and supporting innovation across industries.