Understanding the Properties and Synthesis of 2-Chloro-3,6-difluorobenzaldehyde
For chemists and researchers involved in the synthesis of fine chemicals, understanding the fundamental properties and production methods of key intermediates is essential. 2-Chloro-3,6-difluorobenzaldehyde (CAS: 261762-39-4) is a prime example of such a compound, playing a critical role in various downstream applications, particularly in pharmaceuticals and agrochemicals.
This aromatic aldehyde is characterized by its appearance as a white to off-white crystalline powder. Its physical properties, such as a melting point in the range of 46-50°C and a boiling point of approximately 206.4°C, are important considerations for handling and reaction optimization. The molecular formula C7H3ClF2O and a molecular weight of 176.55 g/mol provide its fundamental chemical identity. The presence of both chlorine and fluorine atoms on the benzene ring contributes to its unique reactivity profile, making it a valuable substrate for a range of organic transformations.
The synthesis of 2-Chloro-3,6-difluorobenzaldehyde typically involves multi-step chemical processes. While specific industrial methods vary, common approaches might include the functionalization of halogenated benzene derivatives. For instance, lithiation of a suitable difluorobenzene precursor followed by reaction with a formylating agent like N,N-dimethylformamide is a known route to introduce the aldehyde group. Ensuring high purity, often exceeding 99.0%, is critical for its efficacy in subsequent synthetic steps.
When you are looking to buy 2-chloro-3,6-difluorobenzaldehyde, it is advantageous to source from a reliable manufacturer and supplier that can provide detailed specifications and consistent quality. Understanding the price of 2-chloro-3,6-difluorobenzaldehyde from a reputable supplier in China, like NINGBO INNO PHARMCHEM CO.,LTD., ensures you obtain a high-grade product vital for your research and production needs. This commitment to quality and supply chain integrity makes us a preferred partner for chemical procurement.
Perspectives & Insights
Molecule Vision 7
“For instance, lithiation of a suitable difluorobenzene precursor followed by reaction with a formylating agent like N,N-dimethylformamide is a known route to introduce the aldehyde group.”
Alpha Origin 24
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Future Analyst X
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