4-Nitrophenyl Trifluoroacetate, identified by its CAS number 658-78-6, is a compound of significant interest in the chemical sciences due to its unique properties and a broad spectrum of applications. This organic ester, often recognized by its synonyms such as trifluoroacetic acid 4-nitrophenyl ester or Sakakibara's Reagent, serves as a valuable tool in various research and industrial settings. Understanding its physical and chemical characteristics is key to appreciating its utility.

The compound typically appears as a white to off-white crystalline powder. Its melting point generally falls within the range of 34-40°C, indicating its solid state under standard laboratory conditions. Chemically, it is characterized by the presence of a trifluoroacetate group attached to a 4-nitrophenyl moiety. This structure imparts enhanced electrophilicity, making it a potent acylating agent. This reactivity is fundamental to many of its applications, including its use in the formation of activated esters and its role in peptide synthesis.

The 4-nitrophenyl trifluoroacetate applications are diverse. It is widely employed in organic synthesis as an efficient acylating agent. Beyond this, it finds utility in analytical chemistry, particularly in enzyme kinetic studies where the release of p-nitrophenol can be monitored spectrophotometrically. Furthermore, its role in bioconjugation techniques allows for the attachment of molecules to surfaces or other biomolecules, which is crucial in areas like targeted drug delivery and diagnostics.

For those seeking to procure this valuable chemical, considering a reputable 4-nitrophenyl trifluoroacetate manufacturer is crucial. NINGBO INNO PHARMCHEM CO.,LTD. is a prominent 4-nitrophenyl trifluoroacetate supplier that offers the product with guaranteed high purity. When evaluating the price, it's important to consider the quality and consistency that a trusted supplier provides. The availability of high purity 4-nitrophenyl trifluoroacetate from NINGBO INNO PHARMCHEM CO.,LTD. ensures that researchers can achieve reproducible results in their experimental work. If you aim to buy 4-nitrophenyl trifluoroacetate for your laboratory or industrial needs, NINGBO INNO PHARMCHEM CO.,LTD. offers a reliable source for this essential compound.