Tetramethylammonium Fluoride Tetrahydrate (TMAF·4H2O), bearing the CAS number 17787-40-5, is a compound of significant interest in various chemical disciplines. Its unique combination of properties as a fluoride source and a weak base makes it a versatile reagent for synthetic chemists. NINGBO INNO PHARMCHEM, a distinguished chemical manufacturer in China, offers this compound with a purity of 99% min, ensuring its suitability for a wide array of applications.

The molecular structure of TMAF·4H2O contributes to its valuable chemical behavior. As a quaternary ammonium salt, it readily dissociates in solution, providing free fluoride ions and tetramethylammonium cations. The fluoride ion is a nucleophile and a base, enabling its use in fluorination reactions and as a catalyst in various organic transformations. These reactions are critical for modifying the properties of organic molecules, such as enhancing lipophilicity, increasing metabolic stability, and altering electronic characteristics.

Key applications of TMAF·4H2O include its use as a fluorinating agent in the synthesis of organofluorine compounds, which are prevalent in pharmaceuticals and agrochemicals. For instance, it can participate in nucleophilic substitution reactions to replace halogens or other leaving groups with fluorine. Additionally, its role as a weak base is exploited for deprotection reactions, particularly the removal of silyl protecting groups from alcohols, and in various coupling and condensation reactions. Many research labs and production facilities buy this chemical for its multifaceted utility.

The tetrahydrate form of TMAF·4H2O offers an advantage in terms of handling and storage compared to its anhydrous counterpart, contributing to safer and more convenient use in laboratory and industrial settings. NINGBO INNO PHARMCHEM prioritizes quality control throughout its manufacturing process to deliver a product that consistently meets the high expectations of its clients.

For those seeking to purchase Tetramethylammonium Fluoride Tetrahydrate, NINGBO INNO PHARMCHEM provides a reliable source with a commitment to quality and customer service. Our goal is to supply the chemical building blocks that drive innovation across diverse industries. Reach out to us to learn more about how our products can support your research and manufacturing needs.