The utility of any chemical intermediate is largely defined by its inherent properties. 4-(Difluoromethoxy)benzenesulfonamide, a compound increasingly recognized for its potential, possesses a unique set of characteristics that make it a valuable asset in chemical synthesis and material science. Understanding these properties is key to unlocking its full application potential.

At its core, 4-(Difluoromethoxy)benzenesulfonamide is an organic compound belonging to the benzenesulfonamide class, notable for the presence of a difluoromethoxy group. This fluorinated moiety significantly influences the molecule's electronic distribution and polarity, which in turn affects its reactivity and interaction with other chemical species. The compound typically presents as a white to almost white powder or crystal, indicating a solid state at room temperature, which is common for such organic molecules.

Key physical and chemical properties reported for 4-(Difluoromethoxy)benzenesulfonamide include a melting point in the range of 110-115 °C and a boiling point of approximately 344.8 °C. These parameters are crucial for determining appropriate reaction conditions and purification methods in synthetic processes. The density is recorded as 1.452 g/cm³, and the index of refraction as 1.507. These measurements provide essential data for material characterization and quality control.

For practical applications, the purity of the intermediate is paramount. 4-(Difluoromethoxy)benzenesulfonamide is generally supplied with an assay of ≥98.0% (HPLC), ensuring a high degree of chemical integrity. This high purity is essential for minimizing side reactions and obtaining reliable results in complex synthetic pathways, particularly in demanding fields like pharmaceutical development and advanced material synthesis. The moisture content is typically kept low, at ≤0.2%.

From NINGBO INNO PHARMCHEM CO.,LTD., users can expect comprehensive documentation, including Safety Data Sheets (SDS) and Product Specifications (PS), which detail safe handling, storage (often recommended at 2-8 °C), and disposal procedures. These resources, along with Certificates of Analysis (COA), ensure that users have all the necessary information to utilize 4-(Difluoromethoxy)benzenesulfonamide effectively and safely in their chemical applications, from laboratory research to industrial-scale production.