Tris Base (CAS 77-86-1), also known as Tromethamine, is a fundamental organic compound with a unique set of chemical properties that make it invaluable across various scientific and industrial sectors. As a leading manufacturer, NINGBO INNO PHARMCHEM CO.,LTD. provides high-quality Tris Base and is committed to educating our clients on its characteristics, synthesis, and safe handling practices.

Chemically, Tris Base is an amine and a triol, with the formula (HOCH2)3CNH2. It appears as a white crystalline powder, readily soluble in water and ethanol. Its melting point typically falls between 167-172°C, and it has a density of approximately 1.353 g/cm³. A key characteristic is its pKa of around 8.1 at 25°C, which determines its effectiveness as a buffer in the pH range of 7 to 9. This pH range is crucial for biological systems, making Tris Base a staple in laboratories for applications like gel electrophoresis (TAE/TBE buffers), enzyme assays, and maintaining cellular culture environments.

Industrially, Tris Base is commonly synthesized through the condensation of nitromethane with formaldehyde under basic conditions, followed by hydrogenation. This process, carried out by experienced chemical manufacturers, ensures the production of a high-purity product suitable for demanding applications. NINGBO INNO PHARMCHEM CO.,LTD. employs advanced synthesis and purification techniques to guarantee the quality and consistency of our Tris Base.

Safe handling of Tris Base is essential in any laboratory or industrial setting. While generally considered safe when handled properly, it is a chemical that can be irritating to the skin, eyes, and respiratory tract. Standard laboratory safety precautions should be followed, including wearing appropriate personal protective equipment (PPE) such as gloves, safety glasses, and lab coats. Good ventilation is also recommended, especially when handling large quantities or fine powders. Always refer to the Material Safety Data Sheet (MSDS) provided by your supplier for detailed safety information and emergency procedures. Proper storage, typically in a cool, dry place in tightly sealed containers, is also vital to maintain product integrity.

For those looking to buy Tris Base with confidence, partnering with a reputable Tris Base manufacturer and supplier like NINGBO INNO PHARMCHEM CO.,LTD. ensures you receive a product that is not only of high purity but also accompanied by essential safety and technical data. Understanding the properties and synthesis of Tris Base empowers users to handle and utilize it effectively and safely. Contact us to learn more about our high-quality Tris Base and our commitment to safety and customer support.