Exploring the Versatility of N-Succinimidyl Myristate in Organic Synthesis
Organic synthesis is the art and science of creating complex molecules from simpler precursors. In this field, the availability of versatile reagents with specific reactivity is crucial for success. N-Succinimidyl Myristate (CAS 69888-86-4) emerges as a highly valuable compound due to its reactive N-hydroxysuccinimide ester group, making it a powerful tool for various synthetic transformations. As a dedicated chemical supplier in China, we provide access to this key intermediate for your synthetic needs.
The primary utility of N-Succinimidyl Myristate in organic synthesis stems from its activated ester functionality. The N-hydroxysuccinimide (NHS) ester is an excellent leaving group, rendering the carbonyl carbon susceptible to nucleophilic attack. This makes N-Succinimidyl Myristate an effective acylating agent, readily reacting with nucleophiles such as amines, alcohols, and thiols to form amide, ester, and thioester bonds, respectively. The efficiency and specificity of these reactions are highly valued in multistep syntheses.
One of the most prominent applications in organic synthesis is the introduction of the myristoyl group (a C14 fatty acid chain). This long hydrophobic chain can be appended to various molecular scaffolds to modify their physical and chemical properties. For example, attaching the myristoyl group can increase a compound's solubility in organic solvents or its interaction with lipophilic environments. This is often employed in the synthesis of complex lipids, modified peptides, and drug conjugates.
Furthermore, N-Succinimidyl Myristate can serve as a precursor in the synthesis of more complex organic molecules. Its well-defined reactivity allows for controlled coupling reactions, making it a versatile building block in combinatorial chemistry and the development of novel chemical entities. The stability of the formed amide bond contributes to the integrity of the synthesized molecules.
As a leading supplier in China, we understand the demands of modern organic synthesis. Our N-Succinimidyl Myristate is produced to high purity standards, ensuring reliable performance in your reactions. Whether you are looking to acylate amines, synthesize complex lipids, or develop new molecular architectures, N-Succinimidyl Myristate offers the versatility and reactivity required to achieve your synthetic goals. Partner with us to equip your laboratory with this essential organic synthesis reagent.
The primary utility of N-Succinimidyl Myristate in organic synthesis stems from its activated ester functionality. The N-hydroxysuccinimide (NHS) ester is an excellent leaving group, rendering the carbonyl carbon susceptible to nucleophilic attack. This makes N-Succinimidyl Myristate an effective acylating agent, readily reacting with nucleophiles such as amines, alcohols, and thiols to form amide, ester, and thioester bonds, respectively. The efficiency and specificity of these reactions are highly valued in multistep syntheses.
One of the most prominent applications in organic synthesis is the introduction of the myristoyl group (a C14 fatty acid chain). This long hydrophobic chain can be appended to various molecular scaffolds to modify their physical and chemical properties. For example, attaching the myristoyl group can increase a compound's solubility in organic solvents or its interaction with lipophilic environments. This is often employed in the synthesis of complex lipids, modified peptides, and drug conjugates.
Furthermore, N-Succinimidyl Myristate can serve as a precursor in the synthesis of more complex organic molecules. Its well-defined reactivity allows for controlled coupling reactions, making it a versatile building block in combinatorial chemistry and the development of novel chemical entities. The stability of the formed amide bond contributes to the integrity of the synthesized molecules.
As a leading supplier in China, we understand the demands of modern organic synthesis. Our N-Succinimidyl Myristate is produced to high purity standards, ensuring reliable performance in your reactions. Whether you are looking to acylate amines, synthesize complex lipids, or develop new molecular architectures, N-Succinimidyl Myristate offers the versatility and reactivity required to achieve your synthetic goals. Partner with us to equip your laboratory with this essential organic synthesis reagent.
Perspectives & Insights
Agile Reader One
“N-Succinimidyl Myristate (CAS 69888-86-4) emerges as a highly valuable compound due to its reactive N-hydroxysuccinimide ester group, making it a powerful tool for various synthetic transformations.”
Logic Vision Labs
“As a dedicated chemical supplier in China, we provide access to this key intermediate for your synthetic needs.”
Molecule Origin 88
“The primary utility of N-Succinimidyl Myristate in organic synthesis stems from its activated ester functionality.”