What is 1-Fluoro-10-iododecane? Applications in Organic Synthesis
In the expansive field of organic chemistry, specialized intermediates are the cornerstone of innovation, enabling the creation of complex molecules for diverse applications. 1-Fluoro-10-iododecane is one such compound, offering unique structural features that make it a valuable tool for synthetic chemists. As a leading manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. is pleased to provide detailed information on this important chemical.
Chemical Identity and Properties
1-Fluoro-10-iododecane, with the CAS number 512783-29-8, is a halogenated alkane with the molecular formula C10H20FI. Its structure consists of a ten-carbon chain with a fluorine atom at one end and an iodine atom at the other. This difunctionalization is key to its utility. Physically, it is a colorless transparent liquid with a density of approximately 1.3 g/mL. Its relatively high boiling point (around 283.7°C) and refractive index (1.477) are important parameters for its handling and use in synthetic reactions. The chemical itself is typically supplied with a high assay of ≥99.0%, ensuring high purity for critical applications, and a moisture content of ≤0.05% for stability.
Key Applications in Organic Synthesis
The primary value of 1-Fluoro-10-iododecane lies in its role as an organic synthesis intermediate. Its two distinct halogen functionalities allow for sequential or selective reactions:
- Introduction of Fluorine: Fluorine atoms are highly sought after in drug discovery and materials science due to their ability to enhance lipophilicity, metabolic stability, and binding affinity. Using 1-Fluoro-10-iododecane allows chemists to strategically incorporate a fluorine atom into a molecule.
- Versatile Iodine Reactivity: The iodine atom is an excellent leaving group for nucleophilic substitutions and is highly reactive in various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, Heck). This enables the formation of complex carbon-carbon bonds, crucial for building intricate molecular structures.
- Building Block for Complex Molecules: Researchers can utilize this compound as a bifunctional linker or as a starting point for synthesizing more complex fluoro-iodo compounds or other difunctionalized alkanes.
Sourcing with Confidence from NINGBO INNO PHARMCHEM CO.,LTD.
When you choose to buy 1-Fluoro-10-iododecane, selecting a reliable supplier is crucial. As a prominent manufacturer in China, we guarantee product quality, competitive prices, and dependable supply. Our efficient production processes and stringent quality control ensure that you receive a product that meets your exact specifications. We offer flexible packaging solutions, including 200 kg drums, and provide global shipping to facilitate your procurement needs. Making a purchase from us means investing in the success of your research.
Conclusion
1-Fluoro-10-iododecane is an indispensable tool for modern organic synthesis. NINGBO INNO PHARMCHEM CO.,LTD. is your trusted partner for high-purity, reliably supplied chemical intermediates. Contact us to learn more about its applications and to secure your supply.
Perspectives & Insights
Logic Thinker AI
“In the expansive field of organic chemistry, specialized intermediates are the cornerstone of innovation, enabling the creation of complex molecules for diverse applications.”
Molecule Spark 2025
“1-Fluoro-10-iododecane is one such compound, offering unique structural features that make it a valuable tool for synthetic chemists.”
Alpha Pioneer 01
“Chemical Identity and Properties1-Fluoro-10-iododecane, with the CAS number 512783-29-8, is a halogenated alkane with the molecular formula C10H20FI.”