What is 2-Isopropylimidazole? A Comprehensive Guide for Chemical Professionals
For chemical professionals, understanding the properties and applications of key intermediates is fundamental to driving innovation and optimizing manufacturing processes. 2-Isopropylimidazole (CAS 36947-68-9) is one such compound that warrants closer examination due to its versatility and growing importance across various sectors. This guide aims to provide a comprehensive overview of 2-Isopropylimidazole, covering its chemical identity, physical and chemical properties, synthesis routes, and its critical roles as an organic synthesis intermediate and an epoxy resin curing agent.
Chemically, 2-Isopropylimidazole is a substituted imidazole derivative. Its molecular formula is C6H10N2, with a molecular weight of 110.157 g/mol. The presence of the isopropyl group (-CH(CH3)2) attached to the second carbon atom of the imidazole ring distinguishes it and imparts specific solubility and reactivity characteristics. Typically, it appears as a white to off-white crystalline powder, with a melting point in the range of 56-62°C (or sometimes cited as 125-134°C depending on purity and source). Its boiling point is approximately 258.0°C at 760 mmHg, and it possesses a flash point of around 114.5°C, indicating moderate flammability.
The synthesis of 2-Isopropylimidazole generally involves reactions that form the imidazole ring with the isopropyl substituent in place. Common methods might include condensation reactions of appropriate precursors. For example, the reaction between isobutyraldehyde, glyoxal, and ammonia derivatives can lead to the formation of substituted imidazoles. Industrial production focuses on achieving high yields and purity, often aiming for an assay of ≥99.0% to meet the demands of its applications.
One of the primary applications of 2-Isopropylimidazole is as an intermediate in organic synthesis. Its imidazole structure allows it to act as a nucleophile or a building block for creating more complex heterocyclic compounds, which are vital in pharmaceuticals, agrochemicals, and specialty materials. When researchers need to buy 2-Isopropylimidazole for custom synthesis projects, they look for suppliers that offer consistent quality and reliable documentation.
Another significant role of 2-Isopropylimidazole is its function as a curing agent for epoxy resins. Its latent catalytic properties mean that it can initiate polymerization and cross-linking upon heating, offering an extended pot life at ambient temperatures. This characteristic is highly valued in applications requiring precise application and controlled curing, such as in high-performance adhesives, coatings, and composite manufacturing. For professionals in these fields, identifying a dependable '2-Isopropylimidazole supplier' ensures the integrity and performance of their final products.
In conclusion, 2-Isopropylimidazole is a compound of significant utility in both research and industrial applications. Its dual role as a versatile organic intermediate and an effective epoxy curing agent makes it a sought-after chemical. Understanding its properties and applications, and securing it from reputable manufacturers and suppliers, is key to harnessing its full potential.
Perspectives & Insights
Core Pioneer 24
“When researchers need to buy 2-Isopropylimidazole for custom synthesis projects, they look for suppliers that offer consistent quality and reliable documentation.”
Silicon Explorer X
“Another significant role of 2-Isopropylimidazole is its function as a curing agent for epoxy resins.”
Quantum Catalyst AI
“Its latent catalytic properties mean that it can initiate polymerization and cross-linking upon heating, offering an extended pot life at ambient temperatures.”