In the demanding world of chemical research and manufacturing, securing high-quality, reliable chemical intermediates is fundamental to success. For professionals engaged in organic synthesis, pharmaceuticals, and agrochemicals, 4-Bromo-2-chloro-1-iodobenzene (CAS: 31928-47-9) stands out as a particularly valuable compound. Its unique trifunctional halogenation makes it a versatile organic synthesis building block. This article serves as a guide for procurement managers and R&D scientists on the properties and applications of this crucial intermediate, and crucially, where to source it effectively from a leading manufacturer in China.

The Chemical Identity and Significance of 4-Bromo-2-chloro-1-iodobenzene

4-Bromo-2-chloro-1-iodobenzene is a halogenated aromatic compound distinguished by the presence of three different halogen atoms attached to a benzene ring: iodine, bromine, and chlorine. This specific arrangement (C6H3BrClI) grants it a unique reactivity profile. The differing electronegativities and bond strengths of the carbon-halogen bonds (C-I being the most reactive, followed by C-Br, then C-Cl) allow for highly selective chemical reactions. This selectivity is a significant advantage in complex syntheses, particularly in metal-catalyzed cross-coupling reactions such as Suzuki, Stille, and Sonogashira couplings. Such precision is often required when developing novel pharmaceuticals or specialized agrochemicals.

Researchers and procurement professionals looking to buy 4-bromo-2-chloro-1-iodobenzene are typically seeking an intermediate that can facilitate efficient molecular construction. Its physical form—often a white to yellow solid with a melting point around 35°C—makes it practical for handling in various laboratory and industrial settings. When stored properly (in a cool, dry, dark place), the compound exhibits good stability, ensuring its utility over time. The ability to perform sequential reactions at specific halogen sites makes it a preferred choice for complex synthetic targets.

Applications Driving the Need for Quality Intermediates

The demand for 4-Bromo-2-chloro-1-iodobenzene stems from its broad utility across several key industries:

  • Pharmaceutical Industry: It is a vital intermediate in the synthesis of Active Pharmaceutical Ingredients (APIs), where molecular precision is paramount for drug efficacy and safety.
  • Agrochemical Sector: This compound plays a role in developing new herbicides, pesticides, and plant growth regulators, contributing to advanced crop protection strategies.
  • Material Science: Its structure lends itself to research in organic electronics, such as in the development of OLEDs and conductive polymers, where tunable electronic properties are desired.
  • Research & Development: As a versatile building block, it is indispensable for exploring novel reaction methodologies and synthesizing new chemical entities in academic and industrial laboratories.

Choosing a Reliable Source: NINGBO INNO PHARMCHEM CO.,LTD.

For reliable access to high-quality CAS 31928-47-9 intermediate, partnering with a trusted supplier in China is essential. NINGBO INNO PHARMCHEM CO.,LTD. is a leading manufacturer and supplier of fine chemical intermediates, dedicated to providing products that meet the highest purity standards. We understand the critical nature of your synthesis projects and are committed to ensuring consistent quality and reliable supply chains for compounds like 4-Bromo-2-chloro-1-iodobenzene.

We offer competitive price points, particularly for bulk orders, and provide comprehensive support, including detailed product specifications and safety data. We invite procurement managers and R&D scientists to request a quote and experience the quality and service that NINGBO INNO PHARMCHEM provides. Contact us today to secure your supply of this indispensable chemical intermediate and advance your chemical innovation efforts.