Boc-Hyp-OH, scientifically known as N-Boc-4-hydroxy-L-proline, is a highly valued derivative of the amino acid hydroxyproline. Its CAS number is 331442-12-7, and it plays an indispensable role in the field of biochemistry and medicinal chemistry. This article delves into why Boc-Hyp-OH is a crucial component for researchers, especially those focused on peptide synthesis and pharmaceutical development.

The primary utility of Boc-Hyp-OH lies in its protected form, where the tert-butoxycarbonyl (Boc) group shields the amine functionality. This protection is essential during multi-step synthesis processes, particularly in the construction of peptide chains. In peptide synthesis, each amino acid must be coupled sequentially, and the Boc group ensures that only the desired reactions occur at each step, preventing unwanted side reactions. The hydroxy group on the proline ring offers further opportunities for structural modification and functionalization, making Boc-Hyp-OH a versatile building block. Researchers often buy Boc-Hyp-OH for its ability to introduce specific structural motifs that can influence a peptide's biological activity, stability, or receptor binding.

As a reliable supplier in China, sourcing high-quality Boc-Hyp-OH is paramount. The purity of this chemical reagent directly impacts the success of complex synthetic procedures. Impurities can lead to truncated peptides, incorrect sequences, or reduced yields, all of which are detrimental to research timelines and budgets. Therefore, selecting a reputable manufacturer or supplier that guarantees a high purity level, often above 98%, is a critical decision for any research institution or pharmaceutical company.

In pharmaceutical research, Boc-Hyp-OH serves as a key intermediate in the synthesis of various active pharmaceutical ingredients (APIs). Its chiral nature and functional groups make it an ideal starting material for creating complex molecular architectures that target specific biological pathways. The demand for Boc-Hyp-OH continues to grow as new therapeutic agents are discovered and developed, underscoring its importance in the drug discovery pipeline. For anyone looking to purchase Boc-Hyp-OH, understanding its specifications and the supplier's quality control measures is key to ensuring the integrity of their research.

In summary, Boc-Hyp-OH (CAS 331442-12-7) is more than just a chemical compound; it is a fundamental tool enabling advancements in peptide synthesis and pharmaceutical innovation. Ensuring a consistent and high-quality supply is vital for researchers worldwide.