Fmoc-Cys(StBu)-OH: A Versatile Reagent for Custom Peptide Synthesis
Fmoc-Cys(StBu)-OH, chemically known as N-alpha-(9-fluorenylmethyloxycarbonyl)-S-(tert-butylthio)-L-cysteine, is a protected amino acid that allows for the controlled incorporation of cysteine residues into custom-synthesized peptides. The Fmoc protecting group facilitates its use in the widely adopted Fmoc/tBu solid-phase peptide synthesis strategy. The tert-butylthio (StBu) group serves to protect the thiol side chain of cysteine, preventing unwanted side reactions such as oxidation or disulfide bond formation during the peptide assembly process.
The demand for custom peptides often involves intricate sequences and specific modifications, where the purity and reactivity of each building block are critical. When scientists need to buy Fmoc-Cys(StBu)-OH, they seek assurance of its quality and consistency. NINGBO INNO PHARMCHEM CO.,LTD., as a dedicated manufacturer of fine chemicals, ensures that their Fmoc-Cys(StBu)-OH meets stringent purity standards, making it ideal for custom synthesis projects where reproducibility is key. Exploring competitive Fmoc-Cys(StBu)-OH prices further enhances the feasibility of these specialized projects.
The specific protection strategy offered by Fmoc-Cys(StBu)-OH is particularly advantageous for creating peptides with disulfide bridges. After the peptide chain is assembled and cleaved from the resin, the S-tert-butylthio group can be readily removed, allowing the free cysteine thiols to form covalent disulfide bonds, which are crucial for the structure and function of many peptides. This capability is vital for researchers working on cyclic peptides or peptides where specific conformational constraints are required.
For those involved in custom peptide synthesis, sourcing high-quality reagents is a fundamental requirement. NINGBO INNO PHARMCHEM CO.,LTD. stands as a reliable manufacturer and supplier, offering Fmoc-Cys(StBu)-OH that meets the rigorous demands of the field. Their commitment to providing essential peptide synthesis reagents supports innovation and accelerates the development of novel peptide-based solutions.
Perspectives & Insights
Quantum Pioneer 24
“This capability is vital for researchers working on cyclic peptides or peptides where specific conformational constraints are required.”
Bio Explorer X
“For those involved in custom peptide synthesis, sourcing high-quality reagents is a fundamental requirement.”
Nano Catalyst AI
“stands as a reliable manufacturer and supplier, offering Fmoc-Cys(StBu)-OH that meets the rigorous demands of the field.”