Amino acids are the fundamental building blocks of life, and their precise manipulation in synthetic chemistry is crucial for advancements in pharmaceuticals, biotechnology, and materials science. Di-tert-butyl Dicarbonate, commonly known as Boc Anhydride, is a key reagent that enables the protection of the amine group in amino acids, paving the way for controlled chemical reactions. At NINGBO INNO PHARMCHEM CO.,LTD., we are a premier manufacturer and supplier of high-purity Boc Anhydride, dedicated to supporting your research and development with top-tier chemical products. If you are asking how to buy Di-tert-butyl Dicarbonate, or searching for a dependable supplier of CAS 24424-99-5, you have come to the right place.

Why Protect Amino Acids with Boc Anhydride?

Amino acids possess both an amino group (-NH2) and a carboxyl group (-COOH), making them zwitterionic and highly reactive. To selectively react either the amino or carboxyl group, the other must be temporarily protected. Boc Anhydride excels at protecting the amine group. The tert-butoxycarbonyl (Boc) group it introduces offers several critical advantages:

  • Selective Protection: The Boc group is specifically added to the amine, leaving the carboxyl group free for reactions like esterification or amide coupling.
  • Acid-Labile Nature: The Boc group can be easily removed under mild acidic conditions (e.g., TFA), a crucial step in liberating the amine functionality after it has served its purpose. This mild deprotection is vital to prevent damage to sensitive peptide chains or other functional groups.
  • Stability: The Boc-protected amine is stable to a wide range of reaction conditions, including nucleophilic attack and basic environments, which allows for broader synthetic flexibility.

For those in academic research or industrial production, understanding the Boc anhydride price and quality is important for budgeting and ensuring experimental success. We are a leading manufacturer in China committed to providing high-quality Di-tert-butyl Dicarbonate.

Applications in Synthesis and Beyond

The utility of Boc Anhydride extends beyond just simple amino acid protection:

  • Peptide Synthesis: It is fundamental in the stepwise assembly of peptides, where each amino acid must be introduced with its amine group protected.
  • Pharmaceutical Development: Many complex drug molecules are synthesized using amine-protected building blocks derived from amino acids.
  • Organic Synthesis: It serves as a versatile reagent in a myriad of organic transformations, enabling targeted reactions on other functional groups within a molecule.

As a premier chemical supplier, NINGBO INNO PHARMCHEM CO.,LTD. ensures that our Di-tert-butyl Dicarbonate meets stringent purity standards, typically exceeding 98% assay by GC. This high purity is critical for reproducible results in your sensitive syntheses.

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  • Uncompromising Quality: Our products are manufactured under strict quality control protocols.
  • Reliable Supply: We offer consistent availability and efficient logistics for timely delivery worldwide.
  • Competitive Pricing: We strive to provide cost-effective solutions for your bulk and research chemical needs.

For the highest quality Di-tert-butyl Dicarbonate to support your amino acid protection and synthesis needs, look no further than NINGBO INNO PHARMCHEM CO.,LTD. Purchase your essential reagents from a trusted partner committed to your success.