Key Considerations When Purchasing Boc-Tyr(Bzl)-OH for Peptide Synthesis
NINGBO INNO PHARMCHEM CO.,LTD. is a dedicated provider of specialized chemical intermediates, including crucial amino acid derivatives for peptide synthesis. Among these, N-Boc-O-benzyl-L-tyrosine (Boc-Tyr(Bzl)-OH) is a frequently utilized building block, essential for researchers engaged in Boc solid-phase peptide synthesis (Boc SPPS). This article outlines key considerations for researchers when they decide to buy Boc-Tyr(Bzl)-OH, emphasizing quality and supplier reliability.
N-Boc-O-benzyl-L-tyrosine is a derivative of tyrosine, where the alpha-amino group is protected by a tert-butoxycarbonyl (Boc) moiety, and the hydroxyl group of the side chain is protected by a benzyl (Bzl) ether. This protective scheme is specifically designed to function within the Boc SPPS workflow. The Boc group is cleaved using mild acidic conditions, typically trifluoroacetic acid (TFA), facilitating the coupling of the next amino acid in the sequence. The O-benzyl group, while stable during Boc deprotection, is removed in the final stages of peptide synthesis, usually alongside cleavage from the resin, often via stronger acidic treatments or hydrogenolysis.
The selection of a reputable supplier is paramount when researchers need to buy Boc-Tyr(Bzl)-OH. High-quality Boc-Tyr(Bzl)-OH ensures the purity of the synthesized peptide, minimizes side reactions, and leads to higher yields. Impurities in the starting material can cascade through the synthesis process, leading to complex purification challenges and potentially compromising the biological activity of the final peptide. Therefore, NINGBO INNO PHARMCHEM CO.,LTD. rigorously controls the quality of its N-Boc-O-benzyl-L-tyrosine, providing detailed documentation to assure researchers of its integrity.
When making a purchase decision, researchers also evaluate the Boc-Tyr(Bzl)-OH price. NINGBO INNO PHARMCHEM CO.,LTD. is committed to offering a competitive Boc-Tyr(Bzl)-OH price, reflecting our understanding of research budget constraints. We believe that access to high-quality chemical reagents should not be a barrier to scientific advancement. Our benzyl protected tyrosine derivative is manufactured to meet exacting standards, providing excellent value for its quality and performance in demanding peptide synthesis applications.
For researchers requiring this critical amino acid derivative, NINGBO INNO PHARMCHEM CO.,LTD. offers a reliable source. We are dedicated to supporting the peptide synthesis community with essential chemical intermediates that enable groundbreaking research and development.
Perspectives & Insights
Molecule Vision 7
“This protective scheme is specifically designed to function within the Boc SPPS workflow.”
Alpha Origin 24
“The Boc group is cleaved using mild acidic conditions, typically trifluoroacetic acid (TFA), facilitating the coupling of the next amino acid in the sequence.”
Future Analyst X
“The O-benzyl group, while stable during Boc deprotection, is removed in the final stages of peptide synthesis, usually alongside cleavage from the resin, often via stronger acidic treatments or hydrogenolysis.”