In the intricate field of peptide synthesis, the precise arrangement and modification of amino acids are critical for creating molecules with desired therapeutic or research functions. 11-Aminoundecanoic Acid (CAS 2432-99-7) has emerged as a valuable component in this domain, not just as a standard amino acid derivative, but as a versatile linker molecule. Its unique structure, featuring a long aliphatic chain separating an amine and a carboxylic acid group, offers specific advantages for chemists and biochemists.

The primary advantage of using 11-Aminoundecanoic Acid in peptide synthesis lies in its ability to act as a spacer or linker. When incorporated into a peptide sequence, the ten methylene groups (-(CH2)10-) between the amine and carboxylic acid provide significant flexibility and distance. This flexibility can be crucial for several reasons: it can help to improve the solubility of a peptide, prevent unwanted aggregation, or orient functional groups in a specific spatial arrangement for optimal biological activity. For example, it can be used to link two peptide fragments, attach a peptide to a solid support, or tether a peptide to another molecule such as a fluorescent tag or a drug moiety.

Researchers often seek out such building blocks when designing complex peptide constructs, including PROTACs (proteolysis-targeting chimeras) or stapled peptides, where precise spacing and conformational control are paramount. The reactivity of both the amine and carboxylic acid groups of 11-Aminoundecanoic Acid allows for its facile incorporation into standard peptide synthesis workflows, typically through amide bond formation. For professionals requiring this specific intermediate for their research, understanding availability and pricing is key.

As a supplier of specialty chemicals, NINGBO INNO PHARMCHEM CO.,LTD. recognizes the growing importance of compounds like 11-Aminoundecanoic Acid in advanced synthesis. For those looking to buy 11-Aminoundecanoic Acid for peptide applications, we offer reliable sourcing and competitive pricing. Our commitment to quality ensures that the product meets the high purity standards required for sensitive biomolecular synthesis, supporting your R&D efforts and facilitating your path from discovery to application. Whether you're synthesizing novel drug candidates or developing advanced biomaterials, consider this bifunctional amino acid as a crucial element in your synthetic strategy.

The long chain of 11-Aminoundecanoic Acid also imparts specific physicochemical properties. Its lipophilic character can influence the overall hydrophobicity of a peptide, potentially affecting its interaction with biological membranes or its pharmacokinetic profile. This makes it a strategic choice when aiming to modify a peptide's absorption, distribution, metabolism, and excretion (ADME) properties. For any peptide synthesis project that requires precise control over spacing, flexibility, or hydrophobicity, 11-Aminoundecanoic Acid offers a powerful tool.