The Role of CAS 122996-47-8 in Advanced Organic Synthesis and Drug Discovery
In the realm of advanced organic synthesis and drug discovery, the availability of high-quality chemical intermediates is critical. CAS 122996-47-8, commonly known as Fmoc-Hyp(tBu)-OH, stands out as a particularly important building block. This N-protected amino acid derivative plays a significant role in constructing complex molecules, especially in the field of peptide chemistry and the development of novel pharmaceuticals. Sourcing this compound from a reliable manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. ensures the purity and efficacy required for demanding scientific applications.
Fmoc-Hyp(tBu)-OH is a derivative of L-hydroxyproline, a non-proteinogenic amino acid that is a crucial component in collagen structure and other biological molecules. The incorporation of modified amino acids like hydroxyproline into synthetic peptides can impart unique structural and functional properties, making them attractive for therapeutic development. The Fmoc protection strategy employed with this compound is a standard in solid-phase peptide synthesis (SPPS), allowing for the sequential addition of amino acids to a growing peptide chain under controlled conditions.
The tert-butyl (tBu) group protecting the hydroxyl functionality of hydroxyproline in Fmoc-Hyp(tBu)-OH is acid-labile, meaning it can be efficiently removed during the final cleavage step of SPPS. This orthogonal protection strategy, where the Fmoc group is base-labile and the tBu group is acid-labile, allows for selective manipulation of the peptide chain without unwanted side reactions. This precision is vital in drug discovery where even minor structural variations can profoundly affect biological activity and safety profiles.
NINGBO INNO PHARMCHEM CO.,LTD. is a distinguished supplier that understands the critical nature of chemical intermediates. Our commitment to providing CAS 122996-47-8 with high purity (typically u226598%) ensures that researchers and pharmaceutical companies can trust the integrity of their synthetic processes. By choosing NINGBO INNO PHARMCHEM CO.,LTD., you gain access to a reliable supply of this essential building block, supporting your efforts in developing next-generation therapeutics and advancing organic chemistry research.
The demand for specialized amino acid derivatives like Fmoc-Hyp(tBu)-OH continues to grow as the field of peptide therapeutics expands. Investing in high-quality materials from reputable manufacturers is not just a matter of convenience; it is a fundamental requirement for achieving successful outcomes in complex synthesis projects. Explore how NINGBO INNO PHARMCHEM CO.,LTD. can be your trusted partner in providing the chemical building blocks you need for innovation.
In summary, CAS 122996-47-8 (Fmoc-Hyp(tBu)-OH) is a high-value intermediate for advanced organic synthesis and drug discovery. Its unique properties and the assurance of quality provided by suppliers like NINGBO INNO PHARMCHEM CO.,LTD. make it an indispensable component for researchers pushing the boundaries of chemical and pharmaceutical innovation.
Fmoc-Hyp(tBu)-OH is a derivative of L-hydroxyproline, a non-proteinogenic amino acid that is a crucial component in collagen structure and other biological molecules. The incorporation of modified amino acids like hydroxyproline into synthetic peptides can impart unique structural and functional properties, making them attractive for therapeutic development. The Fmoc protection strategy employed with this compound is a standard in solid-phase peptide synthesis (SPPS), allowing for the sequential addition of amino acids to a growing peptide chain under controlled conditions.
The tert-butyl (tBu) group protecting the hydroxyl functionality of hydroxyproline in Fmoc-Hyp(tBu)-OH is acid-labile, meaning it can be efficiently removed during the final cleavage step of SPPS. This orthogonal protection strategy, where the Fmoc group is base-labile and the tBu group is acid-labile, allows for selective manipulation of the peptide chain without unwanted side reactions. This precision is vital in drug discovery where even minor structural variations can profoundly affect biological activity and safety profiles.
NINGBO INNO PHARMCHEM CO.,LTD. is a distinguished supplier that understands the critical nature of chemical intermediates. Our commitment to providing CAS 122996-47-8 with high purity (typically u226598%) ensures that researchers and pharmaceutical companies can trust the integrity of their synthetic processes. By choosing NINGBO INNO PHARMCHEM CO.,LTD., you gain access to a reliable supply of this essential building block, supporting your efforts in developing next-generation therapeutics and advancing organic chemistry research.
The demand for specialized amino acid derivatives like Fmoc-Hyp(tBu)-OH continues to grow as the field of peptide therapeutics expands. Investing in high-quality materials from reputable manufacturers is not just a matter of convenience; it is a fundamental requirement for achieving successful outcomes in complex synthesis projects. Explore how NINGBO INNO PHARMCHEM CO.,LTD. can be your trusted partner in providing the chemical building blocks you need for innovation.
In summary, CAS 122996-47-8 (Fmoc-Hyp(tBu)-OH) is a high-value intermediate for advanced organic synthesis and drug discovery. Its unique properties and the assurance of quality provided by suppliers like NINGBO INNO PHARMCHEM CO.,LTD. make it an indispensable component for researchers pushing the boundaries of chemical and pharmaceutical innovation.
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Data Seeker X
“is a distinguished supplier that understands the critical nature of chemical intermediates.”
Chem Reader AI
“Our commitment to providing CAS 122996-47-8 with high purity (typically u226598%) ensures that researchers and pharmaceutical companies can trust the integrity of their synthetic processes.”
Agile Vision 2025
“, you gain access to a reliable supply of this essential building block, supporting your efforts in developing next-generation therapeutics and advancing organic chemistry research.”