For professionals in the pharmaceutical and biotechnology sectors, the consistent availability of high-quality chemical reagents is foundational to successful research and development. Fmoc-L-3-Fluorophenylalanine (CAS 198560-68-8) stands out as a critical building block for advanced peptide synthesis, particularly within the Fmoc Solid-Phase Peptide Synthesis (SPPS) methodology. This article aims to guide R&D scientists and procurement managers on effectively sourcing this essential compound.

Fmoc-L-3-Fluorophenylalanine is a protected amino acid derivative that allows for the precise incorporation of a fluorinated phenylalanine residue into peptide chains. This fluorination can offer significant advantages, including enhanced metabolic stability, improved binding affinity, and modified pharmacokinetic profiles of the resulting peptides. These attributes are highly sought after in the development of novel therapeutic peptides and peptidomimetics.

When sourcing Fmoc-L-3-Fluorophenylalanine, several factors are paramount. Firstly, the purity of the compound, typically specified as ≥97% by HPLC, directly impacts the success and yield of peptide synthesis. Secondly, reliability of supply is crucial; partnering with established manufacturers and distributors ensures consistent availability and avoids disruptions to research timelines. Procurement managers should look for suppliers who offer competitive pricing, clear documentation (such as Certificates of Analysis), and responsive customer service.

The physical form of Fmoc-L-3-Fluorophenylalanine is usually a beige solid or powder, stored under refrigerated conditions (2-8°C) to maintain its integrity. Its application in creating potent antibacterial agents highlights its importance in drug discovery. For those looking to buy this vital reagent, identifying suppliers who can provide both research-scale and bulk quantities is essential. We are a leading manufacturer and supplier, dedicated to providing high-purity Fmoc-L-3-Fluorophenylalanine. Please contact us for a quote and to discuss your specific procurement needs.