Understanding the fundamental chemical properties of a compound is the first step towards unlocking its full potential in research and development. Pentafluorophenol (PFP-OH), identified by CAS number 771-61-9, is a compound whose physical and chemical attributes make it exceptionally useful across several scientific disciplines, most notably in peptide synthesis and as a versatile intermediate. Its unique structure and reactivity have cemented its place in the modern chemist's arsenal.

Pentafluorophenol presents as a white to light yellow crystalline solid. Its physical properties are well-defined: a melting point typically ranging from 34-36°C and a boiling point of 143°C. These characteristics make it relatively easy to handle and store under standard laboratory conditions, contributing to its widespread adoption. The purity of PFP-OH is often critical for its applications, with high purity grades (e.g., ≥99.0% by HPLC) being readily available from reliable suppliers like NINGBO INNO PHARMCHEM CO.,LTD. This ensures that reactions proceed with predictable outcomes, a key factor in both academic research and industrial production.

The primary application that distinguishes Pentafluorophenol is its role as a coupling reagent in peptide synthesis. By forming pentafluorophenyl active esters, PFP-OH facilitates the formation of peptide bonds with remarkable efficiency. This process is crucial for constructing the complex peptide chains that are the building blocks of many important biomolecules and pharmaceuticals. The high coupling rate and low propensity for side reactions offered by PFP-OH-derived esters make it a superior choice for synthesizing peptides with high fidelity. When considering the purchase of Pentafluorophenol, its performance in peptide synthesis is often the key driver.

Beyond its celebrated function in peptide synthesis, Pentafluorophenol serves as a valuable intermediate in a broader spectrum of organic chemistry. Its fluorinated nature and reactive hydroxyl group allow it to participate in various synthetic pathways, including the formation of carbon-carbon bonds, reduction reactions, and the preparation of sulfonamides. These diverse applications highlight the chemical versatility of PFP-OH, making it a key building block for chemists working on novel molecules and materials. As a manufacturer in China, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supplying this essential chemical.

In conclusion, Pentafluorophenol is a compound of significant chemical and practical importance. Its well-defined physical properties and its critical role as an efficient coupling reagent in peptide synthesis, coupled with its broader utility in organic chemistry, make it an indispensable material for researchers and manufacturers alike. For those seeking to procure Pentafluorophenol, NINGBO INNO PHARMCHEM CO.,LTD. offers a dependable source for this essential chemical intermediate.