The Crucial Role of H-D-Lys(Boc)-OMe HCl in Modern Peptide Synthesis
Peptide synthesis is a cornerstone of modern biochemical and pharmaceutical research. It enables the creation of complex peptides that are vital for drug discovery, diagnostics, and therapeutics. Among the key reagents facilitating this intricate process is H-D-Lys(Boc)-OMe HCl, a protected amino acid derivative with the CAS number 66494-53-9. Understanding its properties and sourcing it effectively is paramount for researchers aiming to buy high-quality materials.
H-D-Lys(Boc)-OMe HCl, often referred to as N-epsilon-Boc-D-lysine methyl ester hydrochloride, plays a critical role as a building block. The tert-butoxycarbonyl (Boc) group serves as a protecting group for the epsilon-amino function of lysine, preventing unwanted side reactions during peptide chain elongation. The methyl ester protects the carboxyl group. This specific structure ensures regioselectivity and efficiency in forming peptide bonds. As a D-amino acid derivative, it is particularly valuable for incorporating non-natural stereochemistry into peptides, which can lead to enhanced stability, altered biological activity, or novel therapeutic properties.
When considering the procurement of H-D-Lys(Boc)-OMe HCl, its purity is a critical factor. High-purity grades, typically 98% minimum as confirmed by HPLC, are essential for successful peptide synthesis. Impurities can lead to truncated sequences, incorrect modifications, and ultimately, a compromised final peptide product. Researchers often seek reliable Chinese manufacturers and suppliers who can guarantee consistent quality and competitive pricing for this vital pharmaceutical intermediate.
The applications of H-D-Lys(Boc)-OMe HCl extend beyond basic peptide synthesis. It is utilized in the development of peptide-based drugs, peptide mimetics, and in combinatorial chemistry libraries. Its availability from established suppliers in China ensures that research institutions and pharmaceutical companies have access to the necessary reagents to push the boundaries of scientific innovation. For anyone looking to buy H-D-Lys(Boc)-OMe HCl, partnering with a reputable supplier is key to project success.
Perspectives & Insights
Nano Explorer 01
“Among the key reagents facilitating this intricate process is H-D-Lys(Boc)-OMe HCl, a protected amino acid derivative with the CAS number 66494-53-9.”
Data Catalyst One
“Understanding its properties and sourcing it effectively is paramount for researchers aiming to buy high-quality materials.”
Chem Thinker Labs
“H-D-Lys(Boc)-OMe HCl, often referred to as N-epsilon-Boc-D-lysine methyl ester hydrochloride, plays a critical role as a building block.”