TSTU: Revolutionizing Biomolecular Labeling and Derivatization
The field of biomolecular science constantly seeks advanced reagents to precisely label and modify biological molecules for research, diagnostics, and therapeutics. O-(N-Succinimidyl)-N,N,N',N'-tetramethyluronium tetrafluoroborate, or TSTU, has proven to be a powerful ally in this endeavor, particularly in the realm of chemical derivatization and labeling. As a top supplier of fine chemicals, we recognize the significant impact TSTU has on scientific innovation.
TSTU functions as a potent coupling reagent, facilitating the creation of activated N-hydroxysuccinimidyl esters. These reactive intermediates are pivotal for conjugating various molecules to biomolecules containing amine groups. A prime example of its application is in the post-synthetic chemical derivatization of fluorescent dyes, such as cyanine and rhodamine dyes. By using TSTU, researchers can efficiently attach these dyes to target molecules, creating sophisticated fluorescent labels that are crucial for advanced microscopy, flow cytometry, and various in-vitro diagnostic assays. The resulting conjugates are often water-soluble, enhancing their utility in biological systems.
Beyond fluorescent labeling, TSTU plays a role in the synthesis of critical diagnostic compounds. It is instrumental in preparing N-succinimidyl 4-[18F]fluorobenzoate ([18F]SFB), a key component for developing radiolabeled tracers used in Positron Emission Tomography (PET) imaging. This application highlights TSTU's contribution to cutting-edge medical research, enabling the visualization and study of biological processes in vivo.
The advantages of using TSTU are manifold. Its ability to perform efficiently in aqueous environments makes it a preferred reagent for modifying sensitive biological molecules that may degrade in organic solvents. Furthermore, TSTU generally offers good yields and selectivity, minimizing unwanted side reactions. For scientists and procurement managers looking to purchase TSTU, ensuring a reliable supply of high-purity product is essential for reproducible and accurate experimental outcomes.
In essence, TSTU serves as a versatile and indispensable reagent for chemical derivatization and biomolecular labeling. Its capacity to create stable activated esters and its compatibility with various conditions make it a valuable asset for researchers pushing the boundaries in life sciences and medical imaging. Investing in TSTU is an investment in the precision and innovation of your scientific pursuits.
TSTU functions as a potent coupling reagent, facilitating the creation of activated N-hydroxysuccinimidyl esters. These reactive intermediates are pivotal for conjugating various molecules to biomolecules containing amine groups. A prime example of its application is in the post-synthetic chemical derivatization of fluorescent dyes, such as cyanine and rhodamine dyes. By using TSTU, researchers can efficiently attach these dyes to target molecules, creating sophisticated fluorescent labels that are crucial for advanced microscopy, flow cytometry, and various in-vitro diagnostic assays. The resulting conjugates are often water-soluble, enhancing their utility in biological systems.
Beyond fluorescent labeling, TSTU plays a role in the synthesis of critical diagnostic compounds. It is instrumental in preparing N-succinimidyl 4-[18F]fluorobenzoate ([18F]SFB), a key component for developing radiolabeled tracers used in Positron Emission Tomography (PET) imaging. This application highlights TSTU's contribution to cutting-edge medical research, enabling the visualization and study of biological processes in vivo.
The advantages of using TSTU are manifold. Its ability to perform efficiently in aqueous environments makes it a preferred reagent for modifying sensitive biological molecules that may degrade in organic solvents. Furthermore, TSTU generally offers good yields and selectivity, minimizing unwanted side reactions. For scientists and procurement managers looking to purchase TSTU, ensuring a reliable supply of high-purity product is essential for reproducible and accurate experimental outcomes.
In essence, TSTU serves as a versatile and indispensable reagent for chemical derivatization and biomolecular labeling. Its capacity to create stable activated esters and its compatibility with various conditions make it a valuable asset for researchers pushing the boundaries in life sciences and medical imaging. Investing in TSTU is an investment in the precision and innovation of your scientific pursuits.
Perspectives & Insights
Future Origin 2025
“In essence, TSTU serves as a versatile and indispensable reagent for chemical derivatization and biomolecular labeling.”
Core Analyst 01
“Its capacity to create stable activated esters and its compatibility with various conditions make it a valuable asset for researchers pushing the boundaries in life sciences and medical imaging.”
Silicon Seeker One
“Investing in TSTU is an investment in the precision and innovation of your scientific pursuits.”