Understanding Peptide Building Blocks: The Value of Fmoc-(R)-3-Amino-3-(2,4-dichlorophenyl)propionic Acid
In the intricate world of peptide synthesis, the quality and characteristics of individual amino acid building blocks are paramount to the success of the final peptide product. Specialized amino acids, often referred to as unnatural amino acids, offer chemists the ability to imbue peptides with unique properties not achievable with the standard 20 proteinogenic amino acids. Fmoc-(R)-3-Amino-3-(2,4-dichlorophenyl)propionic acid is a notable example of such a valuable peptide building block, crucial for advancing research in various scientific fields.
This particular unnatural amino acid, designated by CAS number 511272-37-0, is widely utilized due to its specific structural attributes. The Fmoc (9-fluorenylmethoxycarbonyl) protecting group is a standard feature that facilitates its integration into peptide chains using the widely adopted Fmoc solid-phase peptide synthesis (SPPS) methodology. The (R)-stereochemistry at the alpha-carbon is significant for researchers who need to control the chirality of the resulting peptide, as stereoisomers can exhibit vastly different biological activities. Additionally, the presence of a 2,4-dichlorophenyl group in the side chain provides a unique chemical handle that can influence the peptide’s conformation, solubility, and interactions with biological targets, potentially improving its therapeutic efficacy or stability.
For scientists involved in drug discovery and development, the ability to purchase Fmoc-(R)-3-Amino-3-(2,4-dichlorophenyl)propionic acid from reliable peptide synthesis reagent suppliers is essential. These specialized building blocks allow for the design of peptides with tailored properties, such as increased resistance to enzymatic degradation or enhanced binding affinity. Custom peptide synthesis projects often rely on such sophisticated amino acids to create novel peptide sequences for applications ranging from pharmaceuticals to biomaterials. The precision offered by these engineered components is a key driver in modern biochemical research.
NINGBO INNO PHARMCHEM CO.,LTD. is a leading manufacturer and supplier based in China, dedicated to providing high-quality fine chemical intermediates. We specialize in producing essential peptide building blocks like Fmoc-(R)-3-Amino-3-(2,4-dichlorophenyl)propionic acid, ensuring the high purity and chiral integrity required for advanced synthetic applications. By offering these crucial reagents, we empower researchers to explore new possibilities in peptide science and accelerate the development of innovative solutions in medicine and beyond. The value of such meticulously prepared building blocks cannot be overstated in the pursuit of scientific advancement.
Perspectives & Insights
Data Seeker X
“Additionally, the presence of a 2,4-dichlorophenyl group in the side chain provides a unique chemical handle that can influence the peptide’s conformation, solubility, and interactions with biological targets, potentially improving its therapeutic efficacy or stability.”
Chem Reader AI
“For scientists involved in drug discovery and development, the ability to purchase Fmoc-(R)-3-Amino-3-(2,4-dichlorophenyl)propionic acid from reliable peptide synthesis reagent suppliers is essential.”
Agile Vision 2025
“These specialized building blocks allow for the design of peptides with tailored properties, such as increased resistance to enzymatic degradation or enhanced binding affinity.”