For chemists and engineers working in the fine chemical and agrochemical industries, a deep understanding of intermediate compounds is crucial. 2-Amino-4,6-dimethylpyrimidine (CAS: 767-15-7) stands out as a versatile and essential molecule. This article explores its key properties, common synthesis routes, and the importance of sourcing it from reliable manufacturers.

Chemical Profile and Physical Properties

2-Amino-4,6-dimethylpyrimidine is a white crystalline powder with the molecular formula C6H9N3 and a molecular weight of 123.16 g/mol. Its chemical structure features a pyrimidine ring, a heterocyclic aromatic organic compound similar to pyridine, with an amino group at the 2-position and two methyl groups at the 4 and 6 positions. Key physical properties include a melting point range of 151-153 °C and a high assay typically exceeding 99.0%. These characteristics make it well-suited for precise chemical reactions where purity is paramount.

Synthesis Pathways for 2-Amino-4,6-dimethylpyrimidine

The synthesis of 2-Amino-4,6-dimethylpyrimidine often involves the condensation of guanidine with acetylacetone (2,4-pentanedione). This reaction is a classic example of heterocyclic ring formation. Guanidine, a strong base, reacts with the diketone, acetylacetone, under specific conditions to yield the pyrimidine ring structure. Variations in reaction conditions, such as solvent, temperature, and catalysts, can influence yield and purity. For instance, recrystallization from solvents like water or acetone is employed to achieve the desired high purity. Manufacturers continuously optimize these processes to enhance efficiency and reduce costs, enabling them to offer the product at a competitive price.

Applications in Agrochemicals and Beyond

The primary commercial application for 2-Amino-4,6-dimethylpyrimidine is as a crucial intermediate in the synthesis of the herbicide Sulfometuron-Methyl. This herbicide is vital for weed management in various agricultural and forestry settings. Its effectiveness and selectivity rely heavily on the quality of the intermediates used in its production. Beyond agrochemicals, its structure lends itself to potential uses in pharmaceutical research and the development of other specialty organic compounds. If you are looking to buy 2-Amino-4,6-dimethylpyrimidine for such applications, ensuring its consistent quality is essential.

The Role of Manufacturers and Suppliers

Reliable manufacturers play a pivotal role in ensuring the consistent availability and quality of 2-Amino-4,6-dimethylpyrimidine. Companies specializing in fine chemical intermediates, particularly those based in China, often possess advanced synthesis capabilities and economies of scale. When sourcing this compound, it is beneficial to partner with suppliers who can provide:

  • High-purity products (≥99.0% assay).
  • Stable supply chains capable of meeting volume demands.
  • Competitive pricing for bulk purchases.
  • Comprehensive technical data and support.
  • Appropriate packaging (e.g., 25kg drums) and efficient global logistics.

As a dedicated manufacturer and supplier, we are committed to delivering 2-Amino-4,6-dimethylpyrimidine that meets stringent quality standards, supporting the success of your chemical synthesis projects. Our focus on optimized synthesis routes ensures both high purity and cost-effectiveness for our customers.

In summary, 2-Amino-4,6-dimethylpyrimidine is a fundamental intermediate with significant applications. Understanding its properties, synthesis, and the importance of reliable suppliers is key to leveraging its potential in the chemical industry.