Exploring the Synthesis and Chemical Properties of 2,4-Dichloroacetophenone
The field of organic chemistry is built upon the transformation of molecules, where specific compounds serve as foundational elements for more complex structures. Among these, 2,4-dichloroacetophenone, also known as 1-(2,4-dichlorophenyl)ethanone (CAS 2234-16-4), holds a prominent position due to its utility as a versatile intermediate. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to understanding and providing high-quality organic intermediates, and this compound exemplifies that commitment.
The synthesis of 2,4-dichloroacetophenone typically involves established organic reactions, often starting with the appropriate dichlorobenzene derivative. Friedel-Crafts acylation is a common route, where a benzene ring is reacted with an acyl halide or anhydride in the presence of a Lewis acid catalyst. For 1-(2,4-dichlorophenyl)ethanone, this means acylating 1,3-dichlorobenzene. The resulting product, with its distinct arrangement of chlorine atoms and the acetyl group, is characterized by its chemical formula C8H6Cl2O and a molecular weight of approximately 189.04 g/mol. The properties of 2,4-dichloroacetophenone, such as its melting point of 33-34°C and its appearance as white to off-white crystals, are critical for handling and reaction planning.
Beyond its synthesis, the chemical properties of 2,4-dichloroacetophenone make it a valuable reagent. The presence of the ketone functionality and the electron-withdrawing chlorine atoms on the phenyl ring influences its reactivity in various chemical transformations. It can undergo reactions such as reduction, oxidation, and nucleophilic addition, making it a flexible building block in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals. The uses of ethanone 1-(2,4-dichlorophenyl) are diverse, underscoring its importance in advanced organic synthesis.
NINGBO INNO PHARMCHEM CO.,LTD. ensures that its supply of 2,4-dichloroacetophenone meets stringent quality standards, with a typical purity of 97% or higher. This commitment to quality is vital for industries relying on predictable and reproducible results from their chemical inputs. Whether for direct use in research or as an intermediate in large-scale production, the consistent quality of CAS 2234-16-4 is a key advantage.
The ongoing exploration of new synthetic routes and applications for compounds like 2,4-dichloroacetophenone is a testament to the enduring relevance of organic chemistry. As an agrochemical intermediate, its role is particularly significant, contributing to the development of solutions that enhance agricultural productivity and sustainability. NINGBO INNO PHARMCHEM CO.,LTD. remains at the forefront, providing the essential chemical building blocks that drive these advancements.
In essence, the study and provision of 2,4-dichloroacetophenone are critical components of the chemical industry. Its well-defined synthesis and valuable chemical properties make it an indispensable tool for chemists and manufacturers, enabling innovation across multiple sectors.
Perspectives & Insights
Logic Thinker AI
“In essence, the study and provision of 2,4-dichloroacetophenone are critical components of the chemical industry.”
Molecule Spark 2025
“Its well-defined synthesis and valuable chemical properties make it an indispensable tool for chemists and manufacturers, enabling innovation across multiple sectors.”
Alpha Pioneer 01
“The field of organic chemistry is built upon the transformation of molecules, where specific compounds serve as foundational elements for more complex structures.”