Pharmchem Focus: Butyryl Chloride (CAS 141-75-3) in Drug Synthesis
The pharmaceutical industry demands precision and purity at every stage of drug development and manufacturing. For organic synthesis, specific chemical intermediates play crucial roles in building complex molecular structures. Butyryl Chloride, identified by CAS number 141-75-3 and also known as Butanoyl Chloride, stands out as a significant acylating agent in this domain. As a supplier committed to high-quality pharmaceutical intermediates, we highlight the importance of this compound for drug synthesis.
Butyryl Chloride is extensively used as a chemical intermediate in the synthesis of Active Pharmaceutical Ingredients (APIs). Its reactivity allows chemists to introduce the butyryl group into precursor molecules, a step that is often critical for achieving the desired pharmacological activity or modifying the pharmacokinetic properties of a drug. The ability to buy Butyryl Chloride with guaranteed high purity is essential for pharmaceutical research and production, where even minute impurities can affect the safety and efficacy of the final drug product.
The process of synthesizing many pharmaceutical compounds involves sequential acylation reactions, and Butyryl Chloride serves as a reliable reagent for these transformations. For example, it can be used in the preparation of esters and amides, which are common functional groups found in many therapeutic agents. Researchers often seek to buy Butyryl Chloride from manufacturers who can demonstrate stringent quality control measures and provide detailed Certificates of Analysis (CoA) to verify purity levels, often requiring a minimum of 99%.
Beyond its direct role in API synthesis, Butyryl Chloride can also be involved in the production of certain excipients or in the modification of biomolecules for research purposes. The consistent performance and predictable reactivity of high-grade Butyryl Chloride are paramount for ensuring reproducible results in laboratory settings and scalable manufacturing processes.
For pharmaceutical companies and contract manufacturing organizations (CMOs), securing a stable and trustworthy supply chain for critical intermediates like Butyryl Chloride is vital. Identifying chemical manufacturers and suppliers, particularly those with established expertise in producing high-purity organic compounds, is a key strategic consideration. Engaging with suppliers who understand the rigorous demands of the pharmaceutical sector ensures adherence to necessary quality standards and regulatory requirements.
When considering purchasing Butyryl Chloride, buyers should prioritize suppliers who can offer: 1) consistent, high-purity product; 2) comprehensive technical documentation (CoA, SDS); 3) reliable delivery schedules; and 4) competitive pricing for bulk orders. For those sourcing from China, thoroughly vetting potential manufacturers for their quality systems and export experience is crucial.
In conclusion, Butyryl Chloride is a cornerstone intermediate in pharmaceutical synthesis, enabling the creation of vital therapeutic agents. Its precise chemical role and the requirement for high purity make it a compound that demands careful sourcing from reputable chemical suppliers who can meet the exacting standards of the drug development industry.
Perspectives & Insights
Data Seeker X
“The consistent performance and predictable reactivity of high-grade Butyryl Chloride are paramount for ensuring reproducible results in laboratory settings and scalable manufacturing processes.”
Chem Reader AI
“For pharmaceutical companies and contract manufacturing organizations (CMOs), securing a stable and trustworthy supply chain for critical intermediates like Butyryl Chloride is vital.”
Agile Vision 2025
“Identifying chemical manufacturers and suppliers, particularly those with established expertise in producing high-purity organic compounds, is a key strategic consideration.”