In the dynamic landscape of modern agriculture, the development of efficient and targeted crop protection agents is paramount. This advancement is often underpinned by specialized chemical intermediates, and 2-Chloro-6-mercaptobenzoic acid (CAS 20324-51-0) is a prime example of such a critical compound. Its precise synthesis and consistent quality are fundamental for the production of high-performance herbicides, underscoring its significance in the fine chemical industry. NINGBO INNO PHARMCHEM CO., LTD. is a key provider of this essential intermediate.

Unveiling 2-Chloro-6-mercaptobenzoic Acid: Properties and Structure

2-Chloro-6-mercaptobenzoic acid is characterized by its molecular structure, which includes a benzene ring bearing a carboxylic acid group, a chlorine atom at the 2-position, and a mercapto group at the 6-position. This configuration provides it with unique reactivity. Typically appearing as a white or off-white solid powder, it has a melting point around 210-215°C, often with decomposition. Its molecular weight is 188.63 g/mol. The compound exhibits moderate solubility in polar organic solvents like methanol and DMSO, which is advantageous for its use in various chemical synthesis processes. The high purity of this intermediate is essential, particularly for its primary application in the synthesis of pyrithiobac-sodium, a highly effective herbicide. NINGBO INNO PHARMCHEM CO., LTD. is committed to delivering this compound with exceptional purity to meet the stringent requirements of the agrochemical sector.

Efficient Synthesis Strategies for Industrial Needs

The industrial production of 2-Chloro-6-mercaptobenzoic acid predominantly utilizes an efficient two-step synthesis pathway, often beginning with 2,6-dichlorobenzonitrile. The first phase is a thio-reaction, where a sulfur-containing nucleophile, such as sodium sulfide, is introduced to substitute one of the chlorine atoms on the aromatic ring, thus forming the mercapto group. This is followed by a hydrolysis step, which converts the nitrile group into a carboxylic acid. This method is highly regarded for its impressive yields, frequently exceeding 85%, making it a cost-effective choice for large-scale manufacturing. Critical factors for success include the careful selection of reaction solvents (like 1,4-dioxane or dimethylformamide), precise temperature control, and optimized reaction times. NINGBO INNO PHARMCHEM CO., LTD. continuously refines these synthesis techniques to boost efficiency and sustainability, offering high-quality 2-Chloro-6-mercaptobenzoic acid for purchase.

Applications Beyond Herbicide Production

While its principal role is in producing pyrithiobac-sodium, a vital herbicide for global agriculture, the reactive nature of 2-Chloro-6-mercaptobenzoic acid also lends itself to broader applications in organic synthesis. Researchers are exploring its potential as a building block for new pharmaceutical intermediates and advanced materials. For businesses seeking to buy 2-Chloro-6-mercaptobenzoic acid, choosing a reliable supplier like NINGBO INNO PHARMCHEM CO., LTD. ensures access to a product that meets rigorous quality standards and supports ongoing research and development efforts in chemistry.

In summary, 2-Chloro-6-mercaptobenzoic acid is a cornerstone chemical intermediate that significantly contributes to agricultural innovation. Its reliable synthesis and diverse applications highlight the importance of specialized fine chemicals, with NINGBO INNO PHARMCHEM CO., LTD. dedicated to supporting this crucial industry.